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ProGlyProt ID
BC157
Organism Information
Organism Name
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Domain
Bacteria
Classification
Family: Neisseriaceae
Order: Neisseriales
Class: Betaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)
 
 
Genome Sequence(s)
GenBank
EMBL
Organism Additional Information
Neisseria gonorrhoeae is the etiologic agent of the human disease gonorrhoea. It is equipped with a variety of adherence factors that help it in the colonization of diverse microenvironments in the human host. The property of phase and antigenic variation displayed by its type IV pilin enables it to avoid immune system thereby initiating the disease.
 
 
Gene Information
Gene Name
NGO1328
NCBI Gene ID
GenBank Gene Sequence
 
 
Protein Information
Protein Name
CycB
UniProtKB/SwissProt ID
NCBI RefSeq
EMBL-CDS
UniProtKB Sequence
Sequence length
279 AA
Subcellular Location
Periplasm
Function
Cytochrome c5
 
 
Protein Structure
Homology Model
Homology Model File
 
 
Glycosylation Status
Glycosylation Type
O (Ser) linked
Experimentally Validated Glycosite(s) in Full Length Protein
S173
Experimentally Validated Glycosite(s ) in Mature Protein
S173
Glycosite(s) Annotated Protein Sequence
>tr|Q5F759|Q5F759_NEIG1 Putative cytochrome OS=Neisseria gonorrhoeae (strain ATC
C 700825 / FA 1090) GN=NGO1328 PE=4 SV=1 MKQLRDNKAQGSALFTLVSGIVIVIAVLYFLIKL
AGSGSFGDVDATTEAATQTRIQPVGQ LTMGDGIPVGERQGEQIFGKICIQCHAADSNVPNAPKLEHNGDWAPRI
AQGFDTLFQHAL NGFNAMPAKGGAADLTDQELKRAITYMANKSGGSFPNPDEAAPADNAASGTAS*(173)A
PADSAA PAEAKAEDKGAAAPAVGVDGKKVFEATCQVCHGGSIPGIPGIGKKDDWAPRIKKGKETLH KHALEG
FNAMPAKGGNAGLSDDEVKAAVDYMANQSGAKF
Sequence Around Glycosites (21 AA)
PADNAASGTASAPADSAAPAE
Technique(s) used for Glycosylation Detection
Immunoblotting with antiglycan antibodies
Technique(s) used for Glycosylated Residue(s) Detection
Ion-trap MS (mass spectrometry) with electron transfer dissociation (ETD)
 
 
Glycan Information
Glycan Annotation
O-AcHexDATDH (432 Da) and DATDH (229 Da) glycans. DATDH is 2,4 diacetamido-2,4,6 trideoxyhexose.
Technique(s) used for Glycan Identification
LC-ESI-MS/MS with CID (liquid chromatography-electrospray ionization–tandem mass spectrometry with collision-induced dissociation)
 
 
Protein Glycosylation linked (PGL) gene(s)
OST Gene Name
NGO0085
OST NCBI Gene ID
OST GenBank Gene Sequence
OST Protein Name
PglB
OST UniProtKB/ SwissProt ID
OST NCBI RefSeq
OST EMBL-CDS
OST UniProtKB Sequence
OST Genome Context
PGL Additional Links
 
 
Literature
Reference(s)
1) Vik, A., Aas, F.E., Anonsen, J.H., Bilsborough, S., Schneider, A., Egge-Jacobsen, W. and Koomey, M. (2009) Broad spectrum O-linked protein glycosylation in the human pathogen Neisseria gonorrhoeae. Proc Natl Acad Sci U S A, 106, 4447-4452. [PubMed: 19251655]
Additional Comments
Sequon feature: S/T plus low complexity region.
Year of Identification
2009
Year of Validation
2009
 
 
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