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ProGlyProt ID
BC158
Organism Information
Organism Name
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Domain
Bacteria
Classification
Family: Neisseriaceae
Order: Neisseriales
Class: Betaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)
 
 
Genome Sequence(s)
GenBank
EMBL
Organism Additional Information
Neisseria gonorrhoeae is the etiologic agent of the human disease gonorrhoea. It is equipped with a variety of adherence factors that help it in the colonization of diverse microenvironments in the human host. The property of phase and antigenic variation displayed by its type IV pilin enables it to avoid immune system thereby initiating the disease.
 
 
Gene Information
Gene Name
NGO1043
NCBI Gene ID
GenBank Gene Sequence
 
 
Protein Information
Protein Name
Hypothetical protein
UniProtKB/SwissProt ID
NCBI RefSeq
EMBL-CDS
UniProtKB Sequence
Sequence length
114 AA
 
 
Glycosylation Status
Glycosylation Type
O (Ser) linked
Experimentally Validated Glycosite(s) in Full Length Protein
S88
Experimentally Validated Glycosite(s ) in Mature Protein
S88
Glycosite(s) Annotated Protein Sequence
>tr|Q5F7X2|Q5F7X2_NEIG1 Putative uncharacterized protein OS=Neisseria gonorrhoea
e (strain ATCC 700825 / FA 1090) GN=NGO1043 PE=4 SV=1
MKKLLIAAMMAAALA
ACSQEAKQEVKEAAQAVESDVKDTAASAAESAASAVEEAKGQVKD AAADAKASAEEAVTEAKDAAAETKEAVS
*(88)
EAAKDTLNKAADAAQEAADKMKDAAK
Sequence Around Glycosites (21 AA)
DAAAETKEAVSEAAKDTLNKA
Technique(s) used for Glycosylation Detection
Immunoblotting with antiglycan antibodies
Technique(s) used for Glycosylated Residue(s) Detection
The sole hydroxyl-bearing residue in the glycopeptide
 
 
Glycan Information
Glycan Annotation
O-AcHexDATDH (433 Da) and DATDH (229 Da) glycans. DATDH is 2,4 diacetamido-2,4,6 trideoxyhexose.
Technique(s) used for Glycan Identification
LC-ESI-MS/MS with CID (liquid chromatography-electrospray ionization–tandem mass spectrometry with collision-induced dissociation)
 
 
Protein Glycosylation linked (PGL) gene(s)
OST Gene Name
NGO0085
OST NCBI Gene ID
OST GenBank Gene Sequence
OST Protein Name
PglB
OST UniProtKB/ SwissProt ID
OST NCBI RefSeq
OST EMBL-CDS
OST UniProtKB Sequence
OST Genome Context
PGL Additional Links
 
 
Literature
Reference(s)
1) Vik, A., Aas, F.E., Anonsen, J.H., Bilsborough, S., Schneider, A., Egge-Jacobsen, W. and Koomey, M. (2009) Broad spectrum O-linked protein glycosylation in the human pathogen Neisseria gonorrhoeae. Proc Natl Acad Sci U S A, 106, 4447-4452. [PubMed: 19251655]
Additional Comments
Sequon feature: S/T plus low complexity region.
Year of Identification
2009
Year of Validation
2009
 
 
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