ProGP262

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ProGP ID ProGP262
Validation Status Uncharacterized
Organism Information
Organism NamePseudomonas aeruginosa PA7
Domain Bacteria
Classification Family: Pseudomonadaceae
Order: Pseudomonadales
Class: Gammaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI) 381754
Genome Sequence(s)
GenBank CP000744.1
EMBL CP000744
Organism Additional Information Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for nosocomial pneumonia. It possesses a multitude of virulence factors including type IV pili that mediate adhesion to host cells. It is also the major cause of mortality among cystic fibrosis (CF) patients.
Gene Information
Gene NamepilA
Protein Information
Protein NamePillin (Group IV)
Subcellular LocationSecreted
Function Component of pili.
Glycan Information
Glycan Annotation D-Araf (D-arabinofuranose).
Literature
Additional CommentSheared pilins from strain PA7 reacted with anti-LAM antibody, indicating that they are posttranslationally modified with D-Araf.
Year of Identification2008
Year of Identification Month Wise2008.11
Reference1) Kus, J.V., Kelly, J., Tessier, L., Harvey, H., Cvitkovitch, D.G. and Burrows, L.L. (2008) Modification of Pseudomonas aeruginosa Pa5196 type IV Pilins at multiple sites with D-Araf by a novel GT-C family Arabinosyltransferase, TfpW. J Bacteriol, 190, 7464-7478. [PubMed: 18805982]
Author Burrows, L.L.
Research GroupFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Corresponding Author Kus, J.V., Kelly, J., Tessier, L., Harvey, H., Cvitkovitch, D.G. Burrows, L.L.
ContactFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.