ProGP456 (Rv3835)

Home -> ProGPdb -> Search ProGP -> Display data

ProGP ID ProGP456 (Rv3835)
Validation Status Characterized
Organism Information
Organism NameMycobacterium tuberculosis H37Rv
Domain Bacteria
Classification Family: Mycobacteriaceae
Suborder: Corynebacterineae
Order: Actinomycetales
Subclass: Actinobacteridae
Class: Actinobacteria
Division or phylum: "Actinobacteria"
Taxonomic ID (NCBI) 83332
Genome Information
GenBank NC_000962.3
EMBL CP009480
Organism Additional Information It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens.
Gene Information
Gene NameRv3835
NCBI Gene ID 886168
GenBank Gene Sequence NC_000962.3
Protein Information
Protein NameRv3835
UniProtKB/SwissProt ID P96243/P9WKW5
NCBI RefSeq NP_218352
EMBL-CDSCCP46664.3
UniProtKB Sequence >sp|P9WKW5|Y3835_MYCTU Uncharacterized membrane protein Rv3835 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv3835 PE=1 SV=1 AIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHMLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPTPRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
Sequence length 449 AA
Subcellular LocationMembrane
Glycosylation Status
Glycosylation Type O- (Thr) linked
Experimentally Validated Glycosite(s) in Full Length ProteinT373
Glycosite(s) Annotated Protein Sequence >sp|P9WKW5|Y3835_MYCTU Uncharacterized membrane protein Rv3835 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv3835 PE=1 SV=1 AIPAVGRAPERLAGYIASNPVPSTGAKINASFNRVASGDCLMWPDGTPESAAIVSCADEHMLDAPEQDPVDPGDPASPPHGEAEQPLPGPRWPRALRASATRRALLLTALGGLLIAGLVTRFEVAESIDMRTFPGMEYGQNAAPPSPARIQQISEEQCEAAVRRYLGTKFDPNSKFTISMLWPGDRAWRQAGERRMLCGLQSPGPNNQQLAFKGKVADIDQSKVWPAGTCLGIDATTNQPIDVPVDCAAPHAMEVSGTVNLAERFPDALPSEPEQDGFIKDACTRMTDAYLAPLKLRTTTLTLIYPTLTLPSWSAGSRVVACSIGATLGNGGWATLVNSAKGALLINGQPPVPPPDIPEERLNLPPIPLQLPT*(373)PRPAPPAQQLPSTPPGTQHLPAQQPVVTPTRPPESHAPASAAPAETQPPPPDAGAPPATQSPEATPPGPAEPAPAG
Sequence Around Glycosites (21 AA) SGRSIQNKGITPDVPVDQYAD
Average Amino Acid Composition around Glycosite(s)LNLPPIPLQLPT(he)PR
Technique(s) used for Glycosylation DetectionLC-MS (CID)
Technique(s) used for Glycosylated Residue(s) Detection neutral loss MS3, (CID)
Glycan Information
Glycan Annotation Hex
Literature
Year of Identification2014
Year of Identification Month Wise2014.1.31
ReferenceSmith GT, Sweredoski MJ, Hess S (2014) O-linked glycosylation sites profiling in Mycobacterium tuberculosis culture filtrate proteins.J Proteomics, 97:296-306. [PubMed: 23702328]
AuthorSmith, Geoffrey T., Michael J. Sweredoski, and Sonja Hess.
Research GroupProteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, CA, USA
Corresponding Author Sonja Hess.
ContactProteome Exploration Laboratory, Beckman Institute, California Institute of Technology, Pasadena, CA, USA