Latest update: September 24, 2018


ProGT13.15 (Agl18)

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ProGT ID ProGT13.15 (Agl18)
Organism Information
Organism NameMethanococcus maripaludis (strain S2 / LL)
Domain Archaebacteria
Phylum Euryarchaeota
ClassificationFamily: Methanococcaceae
Order: Methanococcales
Class: Methanococci or Methanothermea
Division or phylum: "Euryarchaeota"
Taxonomic ID (NCBI)267377
Genome Information
Gene BankBX950229
EMBLBX950229
Gene Information
Gene Nameagl18 
NCBI Gene ID2761596
NCBI Reference SequenceNC_005791.1.
Protein information
Protein NameAgl18 
UniProtKB/ SwissProt IDQ6M0C0
NCBI Ref SeqWP_011170295.1.
UniProtKB Sequence>tr|Q6M0C0|Q6M0C0_METMP DegT/DnrJ/EryC1/StrS aminotransferase OS=Methanococcus maripaludis (strain S2 / LL) GN=aspB-like1 PE=3 SV=1 MIPIAKPILGNEEISAVTDVLKSGMIAQGKEVELFEREFCEYHNVKYGLAVSNGTTALDV ALKSLKVSSGDEVITTPFTFIASSNCILYQGAKTVFADIDEKTFNIDPNEVLENINSKTK AIIAVHLYGQPADMKALREIADDHKLFLIEDAAQAHGAEFEGKKIGNFGDITTFSFYPTK NMTSSEGGMVVTNNPEIAKISDLIRNHGQAEKYLHTALGYNFRMTNISAAIGRVQLKKVE EWTEKRIKNAKELSKRLSKIDGLSIPYLDKRVRHVFHQYVLRVEADFSLSRDEFSRYLNE NGVGTGIHYPIPVHNQPVYQNLGYDKDECPNSIDAAKKVLSLPVHPSVSLDDIEYITQKI ENRGGVN
EMBL CDSCAF29907.1.
Sequence length367 AA
String267377.MMP0351.
Glycosylation Information
CAZY FamilyNon-GT
Experimental ValidationIn vivo
Additional Information1) Agl18 (MMP0351), Agl19 (MMP0352), and Agl20 (MMP0353) are involved in the synthesis of the UDP-GlcNAc3NAcA from UDP-GlcNAc, the second sugar of N-linked tetrasaccharide.
2) It homolog to WbpE of P. aeruginosa PAO1 and can functionally replace it.  
Litrature
Year Of Validation2015 
Reference Siu, S., Robotham, A., Logan, S. M., Kelly, J. F., Uchida, K., Aizawa, S. I., & Jarrell, K. F. (2015). Evidence that biosynthesis of the second and third sugars of the archaellin tetrasaccharide in the archaeon Methanococcus maripaludis occurs by the same pathway used by Pseudomonas aeruginosa to make a di-N-acetylated sugar. Journal of bacteriology, JB-00040.

Authors Siu, S., Robotham, A., Logan, S. M., Kelly, J. F., Uchida, K., Aizawa, S. I., & Jarrell, K. F.
Research groups1 Department of Biomedical and Molecular Sciences, Queens University, Kingston, Ontario, Canada. 2 Human Health Therapeutics Portfolio, National Research Council, Ottawa, Ontario, Canada. 3 Department of Life Sciences, Prefectural University of Hiroshima, Shobara, Hiroshima, Japan. 4 Department of Biomedical and Molecular Sciences, Queens University, Kingston, Ontario, Canada jarrellk@queensu.ca
Corresponding Author Jarrell, K. F.
ContactsDepartment of Biomedical and Molecular Sciences, Queens University, Kingston, Ontario, Canada.