Latest update: September 24, 2018


ProGT25.3 (PglC)

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ProGT ID ProGT25.3 (PglC)
Organism Information
Organism NameNeisseria meningitidis serogroup B (strain MC58)
Domain Bacteria
Phylum Proteobacteria
ClassificationFamily: Neisseriaceae
Order: Neisseriales
Class: Betaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)122586
Genome Information
Gene BankAE002098
EMBLAE002098
Gene Information
Gene NamepglC 
NCBI Gene ID903279
NCBI Reference SequenceNC_003112.2.
Protein information
Protein NamePglC 
UniProtKB/ SwissProt IDQ7DD75
NCBI Ref SeqWP_002222986.1.
UniProtKB Sequence>tr|Q7DD75|Q7DD75_NEIMB Pilin glycosylation protein PglC OS=Neisseria meningitidis serogroup B (strain MC58) GN=pglC PE=3 SV=1 MLNTFLSPWPCFTQEEADAVSKVLLSNKVNYWTGNECREFEKEFAAFAGTRYAVALANGT LALDVALKAMGIGAGDDVIVTSRTFLASASCIVNAGANPVFADVDLNSQNISAETVKAAL TPTTKAVIVVHLAGMPAEMDGIMALAKEHNLWVIEDCAQAHGAKYKGKSVGSIGHVGAWS FCQDKIMTTGGEGGMVTTNDKTLWEKMWSYKDHGKSYDAVYNHEHAPGFRWLHESFGTNW RMMEMQAVIGRIQLKRLPEWTARRRENAAKLAESLGKFSSIRLVEVADYIGHAQYKFYAF VKPEHLKDGWTRDRIVGELNARKVPCYQGSCSEVYLEKAFDNTPWRPKERLTNAVELGDT SLMFLVHPTLTDDEIAFCKKHIEAVLTEAAR
EMBL CDSAAF42156.1.
Sequence length391 AA
String122586.NMB1821.
Glycosylation Information
Experimental ValidationIn vivo
Function in Glycosylation pathway1) It is a sugar aminotransferase.
Additional Information1) Mutation in pglC gene shows that it plays an important role in pilin glycosylation.  
Litrature
Year Of Validation2001 
Reference Kahler, C. M., Martin, L. E., Tzeng, Y. L., Miller, Y. K., Sharkey, K., Stephens, D. S., & Davies, J. K. (2001). Polymorphisms in pilin glycosylation locus of Neisseria meningitidis expressing class II pili. Infection and immunity, 69(6), 3597-3604.

Authors Kahler, C. M., Martin, L. E., Tzeng, Y. L., Miller, Y. K., Sharkey, K., Stephens, D. S., & Davies, J. K.
Research groupsDepartment of Microbiology, Monash University, Clayton, Australia.
Corresponding Author Davies, J. K.
ContactsDepartment of Microbiology, Monash University, Clayton, Australia.