Latest update: September 24, 2018


ProGT42.1 (Alpha-1,6-glucosyltransferase)

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ProGT ID ProGT42.1 (Alpha-1,6-glucosyltransferase)
ProGT Pathway
Organism Information
Organism NameActinobacillus pleuropneumoniae AP76
Domain Bacteria
Phylum Proteobacteria
ClassificationFamily: Pasteurellaceae
Order: Pasteurellales
Class: Gammaproteobacteria
Phylum: Proteobacteria
Taxonomic ID (NCBI)537457
Glycosylation Information
Sugar Donor SpecificityUDP-Glc 
Acceptor Substrate SpecificityGlucose modifed Hexapeptide DANYTK (labeled with TAMRA at N-terminus)
Experimental ValidationIn vitro
Donor SpecificityUDP-Glc
Function in Glycosylation pathway1) It polymerizes the glucose modified product of NGT catalyzed reaction.
Additional Information1) It is a glucose polymerization enzyme which transfers up to six glucose molecules on the previously glucose modified protein. 
Litrature
Year Of Validation2011 
Reference Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M. (2011). Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NXS/T consensus sequence. Journal of Biological Chemistry, jbc-M111.

Authors Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M.
Research groupsMolecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland
Corresponding Author Aebi, M.
ContactsMolecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland Inst. of Microbiology, Dept. of Biology, ETH Zürich, Wolfgang-Pauli-Str. 10, 8093 Zürich, Switzerland