Latest update: September 24, 2018


ProGTNC16 (PglD)

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ProGT ID ProGTNC16 (PglD)
Organism Information
Organism NameNeisseria gonorrhoeae MS11
Domain Bacteria
Phylum Proteobacteria
ClassificationFamily: Neisseriaceae
Order: Neisseriales
Class: Betaproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)528354
Genome Information
Gene BankCP003909
EMBLCP003909
Gene Information
Gene NamepglD 
Protein information
Protein NamePglD 
Glycosylation Information
CAZY FamilyNon-GT
EC Number (BRENDA)1.1.1.-
Experimental ValidationIn vitro
Function in Glycosylation pathway1) PglD is a NADH-dependent dehydratase, required for the synthesis of Und-PP-diNAcBac in N. gonorrhoeae.
Additional Information1) It shows homology with PglF of C. jejuni and used UDP-GlcNAc as a substrate. 
Litrature
Year Of Validation2011 
Reference Hartley, M. D., Morrison, M. J., Aas, F. E., Børud, B., Koomey, M., & Imperiali, B. (2011). Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N, N?-diacetylbacillosamine. Biochemistry, 50(22), 4936-4948.

Authors Hartley, M. D., Morrison, M. J., Aas, F. E., Børud, B., Koomey, M., & Imperiali, B.
Research groupsDepartments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Corresponding Author Imperiali, B.
ContactsDepartments of Chemistry and Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.