Latest update: September 24, 2018


ProGTNC2 (PglH)

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ProGT ID ProGTNC2 (PglH)
Organism Information
Organism NameCampylobacter jejuni 81116
Domain Bacteria
PhylumProteobacteria
ClassificationFamily: Campylobacteraceae
Order: Campylobacterales
Class: Epsilonproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)407148
Genome Information
Gene BankCP000814.1
EMBLCP000814.1
Gene Information
Gene NamepglH 
Protein information
Protein NamePglH 
Glycosylation Information
CAZY FamilyGT4
EC Number (BRENDA)2.4.1.-
Sugar Donor SpecificityUDP-Glucose 
ProductUndPP-diNAcBac-Glc
Donor SpecificityUDP-Glucose
Function in Glycosylation pathway1) PglH is a GalNAc alpha-1-4 glycosyltransferase
Additional Information1) pglH gene mutant shows the reduced ability to adhere and invade human epithelial Caco-2 cells. 
Litrature
Year Of Validation2004 
Reference Karlyshev, A. V., Everest, P., Linton, D., Cawthraw, S., Newell, D. G., & Wren, B. W. (2004). The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiology, 150(6), 1957-1964.

Authors Karlyshev, A. V., Everest, P., Linton, D., Cawthraw, S., Newell, D. G., & Wren, B. W.
Research groupsLondon School of Hygiene and Tropical Medicine, University of London, Keppel Street, London EC1A 7HT, UK.
Corresponding Author Wren, B. W.
ContactsLondon School of Hygiene and Tropical Medicine, University of London, Keppel Street, London EC1A 7HT, UK.