Latest update: September 24, 2018


ProGT83 (PglLADP1)

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ProGT ID ProGT83 (PglLADP1)
Organism Information
Organism NameAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Clinical ImplicationPathogenic
DomainBacteria
PhylumProteobacteria
ClassificationFamily: Moraxellaceae
Order: Pseudomonadales
Class: Gammaproteobacteria
Phylum: Proteobacteria
Taxonomic ID (NCBI)62977
Genome Information
Gene BankCR543861
EMBLCR543861.1
Gene Information
Gene NamepglL1
NCBI Reference SequenceCAG67081
Protein information
Protein NamePglLADP1 
UniProtKB/ SwissProt IDQ6FFS6
UniProtKB Sequence>sp|Q6FFS6|PGLL1_ACIAD General O-oligosaccharyltransferase OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) GN=pglL1 PE=3 SV=1 MAGSPRVYNSQHCGFSVAVMRFLLLLLTAVLISLAWLSPDHSYPWLTFASEMLSFAAFLS LLALFLNRPLELPRVQLLALPVVFIPMIQWGFGLVVDFSSALLSSAYLLGFWLTMLLGYN LSRSSADRERMFTLSSYLLFAVALLTSLIACIQWLNLESHVPGVMNLYSHRPYANFAQPN NMSTFLILGLLGCLYLAEKQKLKQYYIWPVAALIVFAITLSQSRTAWVFGLFFIIYWTYK SWRYPTHLKRYAVLLWAIGFFAVGLLFPRFTRLIQKLKEGNVVQTSSVVERASAGHERLG IWQQMLDAIHQKPWTGYGWNQTSIAELSSMSSNTIHVWFTSAHNVVLDLLVWNGWLLGGL ITICILIWICWLNVHAKTTESIIACLMVSAVWIHTLLEYPLQYAYFLLPVGFLMGLIQAQ TPDQTARSVPVSVIRSIWVIGIMLLALIWRDYNLYKVNSLRILKNQPANIEIWGSSKILV LTEFDQRLYWLKLSPVAPLTSTELDQIEKMVQNKATPYNLQKYAQLLLANHQFEKAQQQI AYLNRLHKKDYTLQDLQQANASAVESSK
EMBL CDSCAG67081.1
Sequence length568 AA
Subcellular LocationMembrane (Integral component of membrane)
String62977.ACIAD0103
Additional Information1) PglLADP1 is the general O-OTase glycosylating multiple protein targets.
Glycosyltransferase Information
Glycosylation TypeO- (Ser/Thr) linked 
EC Number (BRENDA)2.4.1.-
Mechanism of Glycan TransferEn Bloc
Donor TypeLipid linked sugars
Glycan Information
Glycan transferredPentasaccharide (HexNAc - HexNAc -HexNAc-HexNAc-HexNAc) 
Method of Glycan IndentificationLC-MS, and MS-MS (CID and HCD)
Experimental_strategiesIn vivo 
Acceptor Subtrate Information
Acceptor Substrate name OmpA
ProGPdb ID ProGP412
Acceptor Substrate name Putative secretion protein
ProGPdb ID ProGP497
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP498
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP499
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP503
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP504
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP498
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP502
Acceptor Substrate name Uncharacterized protein
ProGPdb ID ProGP503
Litrature
Year Of Validation2015 
Reference Harding, C.M., Nasr, M.A., Kinsella, R.L., Scott, N.E., Foster, L.J., Weber, B.S., Fiester, S.E., Actis, L.A., Tracy, E.N., Munson Jr, R.S. & Feldman, M. F. (2015). A cinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O?glycosylation of multiple proteins. Molecular microbiology, 96(5), 1023-1041.

Authors Harding, C.M., Nasr, M.A., Kinsella, R.L., Scott, N.E., Foster, L.J., Weber, B.S., Fiester, S.E., Actis, L.A., Tracy, E.N., Munson Jr, R.S. & Feldman, M. F.
Research groups1 Center for Microbial Pathogenesis, The Research Institute at Nationwide Childrens Hospital, Columbus, OH, USA. 2 Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA. 3 Biomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, OH, USA. 4 Department of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2G2, Canada. 5 Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada. 6 Department of Microbiology, Miami University, Oxford, OH, USA
Corresponding Author Feldman, M. F.
ContactsDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2G2, Canada.