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ProGlyProt ID
BU103
Organism Information
Organism Name
Aggregatibacter (Actinobacillus) actinomycetemcomitans Y4 (serotype b)
Domain
Bacteria
Classification
Family: Pasteurellaceae
Order: Pasteurellales
Class: Gammaproteobacteria
Division or phylum: "Proteobacteria"
 
 
Protein Information
Protein Name
37-kDa protein
Subcellular Location
Extracellular
Function
Plays a role in A. actinomycetemcomitans-associated periodontitis, as antigen inducing the release of inflammatory cytokines which are associated with alveolar bone loss. The IL-6-inducing activity was higher than that of LPS.
 
 
Glycosylation Status
Glycosylation Type
Information currently not available with us.
Technique(s) used for Glycosylation Detection
Immunoblotting using anti glycan antibodies.
 
 
Literature
Reference(s)
1) Tani, Y., Tani, M. and Kato, I. (1997) Extracellular 37-kDa antigenic protein from Actinobacillus actinomycetemcomitans induces TNF-alpha, IL-1 beta, and IL-6 in murine macrophages. J Dent Res, 76, 1538-1547. [PubMed: 9294487]
Year of Identification
1997
 
 
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