ProGP1207 (Rv1466)

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ProGP ID ProGP1207 (Rv1466)
Validation Status Characterized
Organism Information
Organism NameMycobacterium tuberculosis
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Corynebacteriales
Family : Mycobacteriaceae
Genus : Mycobacterium
Species : tuberculosis
Strain : H37Rv
Taxonomic ID (NCBI) 83332
Genome Information
GenBank NC_000962.3
Organism Additional Information It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens.
Gene Information
Gene NameRv1466
Protein Information
Protein NameRv1466
UniProtKB/SwissProt ID O53157
NCBI RefSeq NP_215982.1
UniProtKB Sequence >NP_215982.1 hypothetical protein Rv1466 [Mycobacterium tuberculosis H37Rv] MSETSAPAEELLADVEEAMRDVVDPELGINVVDLGLVYGLDVQDGDEGTVALIDMTLTSAACPLTDVIEDQSRSALVGSGLVDDIRINWVWNPPWGPDKITEDGREQLRALGFTV
Function Conserved hypothetical
Glycosylation Status
Glycosylation Type O- (Ser) linked
Experimentally Predicted Glycosites S5
Experimentally Validated Glycosite(s) in Full Length ProteinS5
Experimentally Validated Glycosite(s ) in Mature Protein>NP_215982.1 hypothetical protein Rv1466 [Mycobacterium tuberculosis H37Rv] MSETS*(5)APAEELLADVEEAMRDVVDPELGINVVDLGLVYGLDVQDGDEGTVALIDMTLTSAACPLTDVIEDQSRSALVGSGLVDDIRINWVWNPPWGPDKITEDGREQLRALGFTV
Technique(s) used for Glycosylation DetectionLC-MS/MS analysis
Glycan Information
Glycan Annotation Mannose
Technique(s) used for Glycan Identification nano LC-MS/MS analysis
Literature
Year of Identification2020
ReferenceTucci, P., Portela, M., Chetto, C.R., González-Sapienza, G. and Marín, M., 2020. Integrative proteomic and glycoproteomic profiling of Mycobacterium tuberculosis culture filtrate. PloS one, 15(3), p.e0221837.
Corresponding Author Paula Tucci
ContactBiochemistry Section, Faculty of Sciences, University of the Republic, Montevideo, Uruguay.