ProGP190 (LppN lipoprotein)
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| ProGP ID | ProGP190 (LppN lipoprotein) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium tuberculosis H37Rv |
| Domain | Bacteria |
| Classification | Family: Mycobacteriaceae Suborder: Corynebacterineae Order: Actinomycetales Subclass: Actinobacteridae Class: Actinobacteria Division or phylum: "Actinobacteria" |
| Taxonomic ID (NCBI) | 1773 |
| Genome Information | |
| GenBank | BX842579.1 |
| EMBL | BX842579 |
| Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
| Gene Information | |
| Gene Name | lppN (Rv2270) |
| NCBI Gene ID | 887448 |
| GenBank Gene Sequence | NC_000962 |
| Protein Information | |
| Protein Name | LppN lipoprotein |
| UniProtKB/SwissProt ID | P9WK73 |
| NCBI RefSeq | NP_216786.1 |
| EMBL-CDS | CAB00965.1 |
| UniProtKB Sequence | >sp|P9WK72|LPPN_MYCTO Putative lipoprotein LppN OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=lppN PE=3 SV=1 MRLPGRHVLYALSAVTMLAACSSNGARGGIASTNMNPTNPPATAETATVSPTPAPQSART ETWINLQVGDCLADLPPADLSRITVTIVDCATAHSAEVYLRAPVAVDAAVVSMANRDCAA GFAPYTGQSVDTSPYSVAYLIDSHQDRTGADPTPSTVICLLQPANGQLLTGSARR |
| Sequence length | 175 AA |
| Function | Lipoprotein |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
| Literature | |
| Year of Identification | 2000 |
| Year of Identification Month Wise | 2000.05 |
| Reference | Herrmann, J.L., Delahay, R., Gallagher, A., Robertson, B. and Young, D., 2000. Analysis of post-translational modification of mycobacterial proteins using a cassette expression system. Febs Letters, 473(3), pp.358-362. |
| Corresponding Author | Jean Louis Herrmann |
| Contact | Department of Infectious Diseases and Microbiology, Imperial College School of Medicine, St. Mary's Campus, Norfolk Place, W2 1PG, London, UK. jlh@chu-stlouis.fr |
| Reference | Herrmann, J.L., Delahay, R., Gallagher, A., Robertson, B. and Young, D. (2000) Analysis of post-translational modification of mycobacterial proteins using a cassette expression system. FEBS Lett, 473, 358-362. [PubMed: 10818240] |
| Author | Young, D. |
| Research Group | Department of Infectious Diseases and Microbiology, Imperial College School of Medicine, St. Marys Campus, Norfolk Place, W2 1PG, London |
| Corresponding Author | Herrmann, J.L., Delahay, R., Gallagher, A., Robertson, B. Young, D. |
| Contact | Department of Infectious Diseases and Microbiology, Imperial College School of Medicine, St. Marys Campus, Norfolk Place, W2 1PG, London |