ProGP316 (Srr1)
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| ProGP ID | ProGP316 (Srr1) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Streptococcus agalactiae |
| Domain | Bacteria |
| Classification | Family: Streptococcaceae Order: Lactobacillales Class: Bacilli (or Firmibacteria) Division or phylum: "Firmicutes" |
| Taxonomic ID (NCBI) | 211110 |
| Genome Information | |
| GenBank | NC_004368.1 |
| EMBL | AL766851 |
| Protein Information | |
| Protein Name | Srr1 |
| UniProtKB/SwissProt ID | Q8E473 |
| EMBL-CDS | CAD47188.1 |
| UniProtKB Sequence | >tr|Q8E473|Q8E473_STRA3 Uncharacterized protein OS=Streptococcus agalactiae serotype III (strain NEM316) GN=gbs1529 PE=1 SV=1 MSQKTFGKQLTVVDTKSRVKMHKSGKNWVRTVMSHFNLFKAIKGRATVEADVCIQDVEKE DRLSSGNLTYLKGILAAGALVGGASLTSRVYADETPVVQEQSSSVPTLAEQTEVTVKTTT VQNHQDGTVSKNIIDSNSVSMSESASTSTSESVSMSMSGSTLTSVSESVSTSALTSASES ISTSASESVSKSTSISEVSNILETQASLTDKGRESFSANQIVTESSLVTDAGKNASVSSL IEITKPKSELQTSKMSNESLITPEKSQVMIASDKTGNESLTPTIRLKSVIQPRSMNLMTL SSEMDLIPLEEVSDTEMLGKDVSSELQKVNIALKDNTLSEPGTVKLDSSENLVLNFAFSI ASVNEGDVFTVKLSDNLDTQGIGTILKVQDIMDETGQLLATGSYSPLTHNITYTWTRYAS TLNNIKARVNMPVWPDQRIISKTTSDKQCFTATLNNQVASIEERVQYNSPSVTEHTNVKT NVRSRIMKLDDERQTETYITQINPEGKEMYFASGLGNLYTIIGSDGTSGSPVNLLNAEVK ILKTNSKNLTDSMDQNYDSPEFEDVTSQYSYTNDGSKITIDWKTNSISSTTSYVVLVKIP KQSGVLYSTVSDINQTYGSKYSYGHTNISGDSDANAEIKLLSESASTSASTSASTSASMS ASTSASTSASMSASTSASTSASMSASTSASTSASTSTSTSASTSASTSASTSASMSASTS ASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASMS ASMSASTSASMSASTSASTSASTSASTSASTSASTSASMSASTSASTSASTSASMSASTS ASTSASTSASTSASTSTSTSASTSASTSASTSASMSASTSASTSPSTSASTSASTSASTS ASTSASTSASMSASTSASTSASMSASTSASTSASTSASTSASMSASTSASTSASTSASMS ASTSASTSASTSASTSASTSTSTSASTSASTSASTSASMSASTSASTSASTSASMSASTS ASISASTSASMSASTSASTSASTSASTSASMSASTSASTSASTSASTSASMSASTSASTS ASTSASTSASTSASTSASTSASTSSSTSASTSASTSASTSASMSASTSASTSASMSASTS ASTSASTSASMSASTSSSTSASMSASTSASMSASTSASTSASTSASMSASTSSSTSASMS ASTSASMSASTSASTSASTSASMSASTSASMSATTSASTSVSTSASTSASTSASTSSSSS VTSNSSKEKVYSALPSTGDQDYSVTATALGLGLMTGATLLGRKKSKKDKD |
| Sequence length | 1310 AA |
| Subcellular Location | Surface |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | Lectin binding WITH Swga, Western blot analysis |
| Glycan Information | |
| Glycan Annotation | GlcNAc with hexose sugar |
| Protein Glycosylation linked (PGL) gene(s) | |
| OST ProGT ID | |
| Literature | |
| Reference | Mistou MY, Dramsi S, Brega S, Poyart C, Trieu-Cuot P. (2009) Molecular dissection of the secA2 locus of g B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence. J Bacteriol., 191(13):4195-206. [PubMed: 19395494 ] |
| Author | Mistou MY, Dramsi S, Brega S, Poyart C, Trieu-Cuot P. |
| Research Group | Institut Pasteur, Biological Unit of Gram-Positive Pathogenic Bacteria, URA CNRS 2172, Paris Cedex 15, France. |
| Corresponding Author | Trieu-Cuot P |
| Contact | Institut Pasteur, Biological Unit of Gram-Positive Pathogenic Bacteria, URA CNRS 2172, Paris Cedex 15, France. |
| Reference | Chaze T, Guillot A, Valot B, Langella O, Chamot-Rooke J, Di Guilmi AM, Trieu-Cuot P, Dramsi S, Mistou MY.(2014) O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry. Mass,Mol Cell Proteomics, 13(9), 2168-82. [PubMed: 24797265] |
| Author | Chaze T, Guillot A, Valot B, Langella O, Chamot-Rooke J, Di Guilmi AM, Trieu-Cuot P, Dramsi S, Mistou MY. |
| Research Group | 1 INRA, MICALIS UMR-1319, 78352 Jouy-en-Josas cedex, France; AgroParisTech, MICALIS UMR-1319, 78352 Jouy-en-Josas cedex, France; Institute of Pasteur, Structural and Proteomic Mass Spectrometry Unit, 28 rue du Dr Roux, 75015 Paris, France 2 INRA, PAPPSO, MICALIS UMR-1319, 78352 Jouy en Josas cedex, France 3 INRA, PAPPSO, Plant genetics UMR-320, Ferme du Moulon, 91190 Gif sur Yvette, France; 4 Institut Pasteur, Structural and Proteomic Mass Spectrometry Unit, 28 rue du Dr Roux, 75015 Paris, France; CNRS UMR 3528, Institut Pasteur, 28 rue du Dr Roux, 75015 Paris, France. 5 CEA,Institute of Structural Biology Jean-Pierre Ebel, F-38027 Grenoble, France 6 Institut Pasteur, Unit of Biology of Pathogenic Bacteria in Gram +, 28, rue du Dr Roux, 75015 Paris, France; National Center for Scientific Research, CNRS ERL3526, Paris, France; 7 INRA, MICALIS UMR-1319, 78352 Jouy-en-Josas cedex, France |
| Contact | INRA, MICALIS UMR-1319, 78352 Jouy-en-Josas cedex, France |