ProGP465 (Immunogenic protein MPT63)

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ProGP ID ProGP465 (Immunogenic protein MPT63)
Validation Status Uncharacterized
Organism Information
Organism NameMycobacterium smegmatis mc2-155
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Corynebacteriales
Family : Mycobacteriaceae
Genus : Mycobacterium
Species : smegmatis
Strain : mc(2)155
Taxonomic ID (NCBI) 246196
Genome Information
GenBank CP000480.1
EMBL CP000480.1
Gene Information
Gene NameMsmeg_828
NCBI Gene ID 4537086
GenBank Gene Sequence NC_008596.1
Protein Information
Protein NameImmunogenic protein MPT63
UniProtKB/SwissProt ID A0QQP4
NCBI RefSeq WP_011727224.1
EMBL-CDS ABK74260.1
UniProtKB Sequence >tr|A0QQP4|A0QQP4_MYCS2 Immunogenic protein MPT63 OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=MSMEG_0828 PE=4 SV=1 MKISQLTIAAAAALAISGAAGTAGMATAFAEAAQAAQVSANPLGSQARLENGDVVQAWTI SDLKPSSDPIPYAVQGTLWEATATDEAVSGSVIPIVSNLNARAANGENYRVLFQVATPQG VNPSTLAPGQKTTGKVYFDVTGEAPTTVVYNDGERDLLAWSQTAASTTSPRPAATGSGTS ASTPARTAPVTTAPASNTPATELVPESPAVAPTGAAPAAAPGAGAAATDIPGSTVPPLAE DAADEALAEELTEDLPDELSQDSVTPGESVGTPLPAAVQQAPAAPAPGQPAPAAPGAQDI PAAPAGEVPAAPVTPAPAAPVDGSTTPTVPAGSDAPLTAGGIPTLVPAANPGAPTP
Sequence length 356 AA
Subcellular LocationExtracellular space
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Technique(s) used for Glycosylation DetectionLC-MS (HCD)
Glycan Information
Glycan Annotation Monosaccharide ( mannose)
Protein Glycosylation linked (PGL) gene(s)
OST ProGT IDProGT61 ProGT62
Characterized Accessory Gene(s)Msmeg_5447
Literature
Year of Identification2013
Year of Identification Month Wise2014.3.5
ReferenceLiu, C.F., Tonini, L., Malaga, W., Beau, M., Stella, A., Bouyssié, D., Jackson, M.C., Nigou, J., Puzo, G., Guilhot, C. and Burlet-Schiltz, O., 2013. Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences, 110(16), pp.6560-6565.
Corresponding Author Michel Rivière
ContactUniversity of Toulouse, Paul Sabatier University, Institute of Pharmacology and Structural Biology, F-31077 Toulouse, France;