ProGP714 (SRRP53608)
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ProGP ID | ProGP714 (SRRP53608) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Lactobacillus reuteri ATCC 53608 |
Domain | Bacteria |
Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Lactobacillaceae Genus : Lactobacillus Species : reuteri Strain : 100-23C |
Taxonomic ID (NCBI) | 1598 |
Gene Information | |
Gene Name | srr |
Protein Information | |
Protein Name | SRRP53608 |
Subcellular Location | gastrointestinal tract of numerous vertebrates |
Function | Biofilm formation and adhesion capability |
Glycosylation Status | |
Glycosylation Type | O- (Ser/Thr) linked |
Technique(s) used for Glycosylation Detection | NMR analysis |
Protein Glycosylation- Implication | Lactobacillus reuteri is a gut symbiont inhabiting the gastrointestinal tract of numerous vertebrates. The surface-exposed serine-rich repeat protein (SRRP) is a major adhesin in Gram-positive bacteria. Using lectin and sugar nucleotide profiling of wild-type or L. reuteri isogenic mutants provide different glycan. |
Glycan Information | |
Glycan Annotation | di-GlcNAc |
Technique(s) used for Glycan Identification | MALDI-MS/LC-MS |
Literature | |
Year of Identification | 2019 |
Reference | Latousakis, D., Nepravishta, R., Rejzek, M., Wegmann, U., Le Gall, G., Kavanaugh, D., Colquhoun, I.J., Frese, S., MacKenzie, D.A., Walter, J. and Angulo, J., 2019. Serine-rich repeat protein adhesins from Lactobacillus reuteri display strain specific glycosylation profiles. Glycobiology, 29(1), pp.45-58. |
Corresponding Author | Nathalie Juge |
Contact | The Gut Microbes and Health Institute Strategic Programme, Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UA, UK |