| ProGT ID | ProGT10.7 (PglC) |
| Organism Information | |
| Organism Name | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Epsilonproteobacteria Orders : Campylobacterales Family : Campylobacteraceae Genus : Campylobacter Species : jejuni Subspecies : jejuni Strain : ATCC 700819 / NCTC 11168 |
| Taxonomic ID (NCBI) | 192222 |
| Genome Information | |
| Gene Bank | AL111168.1 |
| EMBL | AL111168.1 |
| Gene Information | |
| Gene Name | pglC |
| NCBI Gene ID | 905415 |
| NCBI Reference Sequence | NC_002163.1. |
| Protein information | |
| Protein Name | PglC |
| UniProtKB/ SwissProt ID | Q0P9D0 |
| NCBI Ref Seq | WP_002852766.1. |
| UniProtKB Sequence | >sp|Q0P9D0|PGLC_CAMJE Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) GN=pglC PE=1 SV=1 MYEKVFKRIFDFILALVLLVLFSPVILITALLLKITQGSVIFTQNRPGLDEKIFKIYKFK TMSDERDEKGELLSDELRLKAFGKIVRSLSLDELLQLFNVLKGDMSFVGPRPLLVEYLPL YNKEQKLRHKVRPGITGWAQVNGRNAISWQKKFELDVYYVKNISFLLDLKIMFLTALKVL KRSGVSKEGHVTTEKFNGKN |
| EMBL CDS | CAL35241.1. |
| Sequence length | 200 AA |
| Subcellular Location | Membrane (Integral component of membrane) |
| String | 192222.Cj1124c. |
| Glycosylation Information | |
| EC Number (BRENDA) | 2.7.8.36 |
| Sugar Donor Specificity | UDP-2-acetamido-4-keto-2,4,6-trideoxy-d-glucose |
| Acceptor Substrate Specificity | UndPP |
| Product | UndPP-diNAcBac |
| Donor Specificity | UDP-2-acetamido-4-keto-2,4,6-trideoxy-d-glucose |
| Function in Glycosylation pathway | 1) PglC is a glycosyl-1-phosphate transferase, required for the first step in the formation of an undecaprenyl-linked heptasaccharide donor in Campylobacter jejuni, it catalyzes the transfer of bacillosamine phosphate to undecaprenyl phosphate to form Und-PP-Bac. |
| Litrature | |
| Year Of Validation | 2006 |
| Reference | Glover, K.J., Weerapana, E., Chen, M.M. and Imperiali, B., 2006. Direct biochemical evidence for the utilization of UDP-bacillosamine by PglC, an essential glycosyl-1-phosphate transferase in the Campylobacter jejuni N-linked glycosylation pathway. Biochemistry, 45(16), pp.5343-5350. |
| Corresponding Author | Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. |