| ProGT ID | ProGT15.21 (Agl15) |
| Organism Information | |
| Organism Name | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2) |
| Domain | Archaebacteria |
| Classification | Phylum : Euryarchaeota Class : Halobacteria Orders : Haloferacales Family : Haloreacaceae Genus : Haloferax Species : volcanii Strain : strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2 |
| Taxonomic ID (NCBI) | 309800 |
| Genome Information | |
| Gene Bank | CP001956.1 |
| EMBL | CP001956.1 |
| Gene Information | |
| Gene Name | agl15 |
| NCBI Reference Sequence | NZ_AOHU01000097.1. |
| Protein information | |
| Protein Name | Agl15 |
| UniProtKB/ SwissProt ID | D4GU68 |
| UniProtKB Sequence | >sp|D4GU68|AGL15_HALVD Probable low-salt glycan biosynthesis flippase Agl15 OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) GN=agl15 PE=3 SV=1 MDLARSSIKLFIANIFGAGLQFLGITFFARELGASQMGVFFLFQALLGIVAIPADFGLRG AVEKRISEGIQPGEYLSSAIILKLIPISLIILSIVVFEQRINGYLGGDFAVYLALAIILQ ETAQLAVSVLKGELRVGETAELNIIRRITWVGGGFLLVSSGLDAEALIYSLLAGMVVTLA WGLSKISTSLKKPSFKNARSLFNYSKYSVVSSIGGYFYSWMDVAIIGIFLTQSHVGAYET AWRVTAITMLFSQAVASTIFPQVSQWSSKNEQQQIESVISNSITPSMLLVIPAFFGILVF SDEIMGIVFGSEFTIASYVLIILAGEKILQSVHVIIGRSLQALNQPGLAARATVISVVLN LILNVILILSFGIVGAAVATALSFAVNTVLHAHYLSSFVSIKFQYSQIGWCTVSSLIMAG VLFGFKTLVGVNSLIQLFIGIFFGMLVYTTITLLYQPIRETAFKNLIRLVPI |
| EMBL CDS | ADE05104.1. |
| Sequence length | 472 AA |
| Subcellular Location | Membrane |
| String | 309800.HVO_2055. |
| Glycosylation Information | |
| CAZY Family | Non-GT |
| Experimental Validation | In vivo |
| Function in Glycosylation pathway | 1) Agl15 act as a flippase, mediating the translocation of low-salt tetrasaccharide-charged DolP across the membrane. |
| Litrature | |
| Year Of Validation | 2013 |
| Reference | Kaminski, L., Guan, Z., Yurist-Doutsch, S. and Eichler, J., 2013. Two distinct N-glycosylation pathways process the Haloferax volcanii S-layer glycoprotein upon changes in environmental salinity. MBio, 4(6), pp.e00716-13. |
| Corresponding Author | Department of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel. |