| ProGT ID | ProGT15.7 (AglM) |
| Organism Information | |
| Organism Name | Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2) |
| Domain | Archaebacteria |
| Classification | Phylum : Euryarchaeota Class : Halobacteria Orders : Haloferacales Family : Haloreacaceae Genus : Haloferax Species : volcanii Strain : strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 /DS2 |
| Taxonomic ID (NCBI) | 309800 |
| Genome Information | |
| Gene Bank | CP001956.1 |
| EMBL | CP001956.1 |
| Gene Information | |
| Gene Name | aglM |
| NCBI Gene ID | 8924832 |
| NCBI Reference Sequence | NZ_AOHU01000097.1. |
| Protein information | |
| Protein Name | AglM |
| UniProtKB/ SwissProt ID | D4GYH5 |
| NCBI Ref Seq | WP_004041409.1. |
| UniProtKB Sequence | >sp|D4GYH5|AGLM_HALVD UDP-glucose 6-dehydrogenase AglM OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) GN=aglM PE=1 SV=1 MELSIIGSGYVGTTIAACFAELGHDVVNVDIDEDIVASLNDGQAPIHEPGLAELVERYAG DRLRATTDYDEILDTDATFLALPTPSTDDGSIDLGAMKTAATSLGETLARKDDSHLVVTK STVVPRTTVDVIGPRIEEASGKRVGDGLDIAMNPEFLREGTAVDDFLSPDKIVLGAQTDR AYETLAEIFAPLVERAGNPPVVKTGISEAEMIKYANNAFLASKISLANDLANICKVFGVD SAEVLESIGLDSRIGSAFLGAGLGWGGSCFPKDTAAIIAAARAQGYEPRLLQAAVDVNDG QPERMLDLLRERFDLDGKRVAVLGLAFKPGTDDIRKSRAILLIQALLDAGADVVGYDPVA TENMRERFPDIDYADSAADALANADAALVATDWDEFAALDDEFDAMRERIVIDGRRIVTR REGLDYESLV |
| EMBL CDS | CAY46591.1. |
| Sequence length | 430 AA |
| String | 309800.HVO_1531. |
| Glycosylation Information | |
| CAZY Family | Non-GT |
| EC Number (BRENDA) | 1.1.1.22 |
| Sugar Donor Specificity | UDP-glucose |
| Experimental Validation | In vivo |
| Product | UDP-glucuronate |
| Donor Specificity | UDP-glucose |
| Function in Glycosylation pathway | 1) AglM functions as a NAD(+) dependent UDP-glucose dehydrogenase. |
| Additional Information | 1) Involved in the formation of the hexuronic acids found at both positions two and three of the N-linked pentasaccharide. |
| Litrature | |
| Year Of Validation | 2010 |
| Reference | Yurist?Doutsch, S., Magidovich, H., Ventura, V.V., Hitchen, P.G., Dell, A. and Eichler, J., 2010. N?glycosylation in Archaea: on the coordinated actions of Haloferax volcanii AglF and AglM. Molecular microbiology, 75(4), pp.1047-1058. |
| Corresponding Author | Department of Life Sciences, Ben Gurion University of the Negev, Beersheva, Israel. |