| ProGT ID | ProGT75.1 (Gtf3) |
| Organism Information | |
| Organism Name | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Streptococcaceae Genus : Streptococcus Species : pneumoniae Strain : ATCC BAA-334 / TIGR4 |
| Taxonomic ID (NCBI) | 170187 |
| Genome Information | |
| Gene Bank | AE005672.3 |
| EMBL | AE005672.3 |
| Gene Information | |
| Gene Name | gtf3 (SP_1768) |
| Protein information | |
| Protein Name | Gtf3 |
| UniProtKB/ SwissProt ID | A0A0H2UR93 |
| NCBI Ref Seq | WP_000766254.1 |
| UniProtKB Sequence | >tr|A0A0H2UR93|A0A0H2UR93_STRPN Uncharacterized protein OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_1768 PE=4 SV=1 MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIASDSPSEMNKRLDGIMA SISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDVVPLMFDSNYYLMKDYLYM YNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDLSLYTPAFKKELFFAGSLERF PDLQNWSQDTPLRVFSNKGEASSSARSLSIEGWKKDEELLLELSKGGFGLVWGTHQNEGE SNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIVDQGLGFMADSLEEVHEIVDKMNLQ EYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLGID |
| EMBL CDS | AAK75843 |
| Sequence length | 336 AA |
| Glycosylation Information | |
| Sugar Donor Specificity | UDP-Glc |
| Acceptor Substrate Specificity | GlcNAc-modified SRR |
| Experimental Validation | In vivo and In vitro |
| Donor Specificity | UDP-Glc |
| Function in Glycosylation pathway | 1) Gtf3 is responsible for the transfer of Glc residue on to the GlcNAc-modified SRR. |
| Additional Information | 1) Gtf3 shows a higher hydrolytic activity toward UDP-Glc compared with UDP-Gal. |
| Litrature | |
| Year Of Validation | 2017 |
| Reference | Jiang, Y.L., Jin, H., Yang, H.B., Zhao, R.L., Wang, S., Chen, Y. and Zhou, C.Z., 2017. Defining the enzymatic pathway for polymorphic O-glycosylation of the pneumococcal serine-rich repeat protein PsrP. Journal of Biological Chemistry, 292(15), pp.6213-6224. |
| Corresponding Author | 1 Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China. |
| Reference | Jiang, Y.L., Jin, H., Yang, H.B., Zhao, R.L., Wang, S., Chen, Y. and Zhou, C.Z., 2017. Defining the enzymatic pathway for polymorphic O-glycosylation of the pneumococcal serine-rich repeat protein PsrP. Journal of Biological Chemistry, 292(15), pp.6213-6224. |
| Corresponding Author | 1 Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China. |