ProGT136 (gttA- putative glycosyltransferase)
| ProGT ID | ProGT136 (gttA- putative glycosyltransferase) |
| Organism Information | |
| Organism Name | Listeria monocytogenes serovar 4b |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Bacillales Family : Listeriaceae Genus : Listeria Species : monocytogenes |
| Taxonomic ID (NCBI) | 1639 |
| Genome Information | |
| Gene Information | |
| Gene Name | gttA |
| Protein information | |
| Protein Name | WTA, LTA |
| Subcellular Location | Cell Wall |
| Function in Native Organism | Cellular invasiveness and virulence |
| Glycosyltransferase Information | |
| Donor Type | UDP-Glc |
| Glycan Information | |
| Glycan transferred | Monosaccharide (Galactose) |
| Method of Glycan Indentification | UPLC-MS/MS |
| Experimental_strategies | In vivo and in vitro |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | WTA/ LTA |
| ProGPdb ID | ProGP1155, ProGP1156 |
| Litrature | |
| Year Of Validation | 2019 |
| Reference | Sumrall, E.T., Shen, Y., Keller, A.P., Rismondo, J., Pavlou, M., Eugster, M.R., Boulos, S., Disson, O., Thouvenot, P., Kilcher, S. and Wollscheid, B., 2019. Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion. PLoS pathogens, 15(10), p.e1008032. |
| Corresponding Author | Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland |