ProGT44 (NGT)
| ProGT ID | ProGT44 (NGT) |
| Organism Information | |
| Organism Name | Yersinia enterocolitica strain 8081 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Phylum | Proteobacteria |
| Classification | Family: Yersiniaceae Order: Enterobacterales Class: Gammaproteobacteria Phylum: Proteobacteria |
| Taxonomic ID (NCBI) | 393305 |
| Genome Information | |
| Gene Bank | AM286415.1 |
| EMBL | AM286415.1 |
| Gene Information | |
| Protein information | |
| Protein Name | NGTÂ |
| Subcellular Location | Cytoplasm |
| Glycosyltransferase Information | |
| Glycosylation Type | N- (Asn) linked |
| CAZY Family | GT41 |
| EC Number (BRENDA) | 2.4.1.- |
| Mechanism of Glycan Transfer | Sequential |
| Acceptor specificity Sequon_1 | NX(S/T) |
| Donor Type | Nucleotide activated sugars |
| Donor Specificity | UDP-Glc and UDP-Gal ( UDP-Glc is preferred over UDP-Gal) |
| Glycan Information | |
| Glycan transferred | Monosaccharides (Glc and Gal)Â |
| Experimental_strategies | In vitro |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Hexapeptide DANYTK (labeled with TAMRA at the N terminus) |
| Litrature | |
| Year Of Validation | 2011Â |
| Reference | Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M. (2011). Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NXS/T consensus sequence. Journal of Biological Chemistry, jbc-M111. |
| Authors | Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M. |
| Research groups | Molecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland |
| Corresponding Author | Aebi, M. |
| Contacts | Molecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland
Inst. of Microbiology, Dept. of Biology, ETH Zürich, Wolfgang-Pauli-Str. 10, 8093 Zürich, Switzerland |