ProGT44 (NGT)
ProGT ID | ProGT44 (NGT) |
Organism Information | |
Organism Name | Yersinia enterocolitica strain 8081 |
Clinical Implication | Pathogenic |
Domain | Bacteria |
Phylum | Proteobacteria |
Classification | Family: Yersiniaceae Order: Enterobacterales Class: Gammaproteobacteria Phylum: Proteobacteria |
Taxonomic ID (NCBI) | 393305 |
Genome Information | |
Gene Bank | AM286415.1 |
EMBL | AM286415.1 |
Gene Information | |
Protein information | |
Protein Name | NGTÂ |
Subcellular Location | Cytoplasm |
Glycosyltransferase Information | |
Glycosylation Type | N- (Asn) linked |
CAZY Family | GT41 |
EC Number (BRENDA) | 2.4.1.- |
Mechanism of Glycan Transfer | Sequential |
Acceptor specificity Sequon_1 | NX(S/T) |
Donor Type | Nucleotide activated sugars |
Donor Specificity | UDP-Glc and UDP-Gal ( UDP-Glc is preferred over UDP-Gal) |
Glycan Information | |
Glycan transferred | Monosaccharides (Glc and Gal)Â |
Experimental_strategies | In vitro |
Acceptor Subtrate Information | |
Acceptor Substrate name | Hexapeptide DANYTK (labeled with TAMRA at the N terminus) |
Litrature | |
Year Of Validation | 2011Â |
Reference | Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M. (2011). Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NXS/T consensus sequence. Journal of Biological Chemistry, jbc-M111. |
Authors | Schwarz, F., Fan, Y. Y., Schubert, M., & Aebi, M. |
Research groups | Molecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland |
Corresponding Author | Aebi, M. |
Contacts | Molecular Biology and Biophysics, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland
Inst. of Microbiology, Dept. of Biology, ETH Zürich, Wolfgang-Pauli-Str. 10, 8093 Zürich, Switzerland |