ProGP1175 (Mpt83)

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ProGP ID ProGP1175 (Mpt83)
Validation Status Characterized
Organism Information
Organism NameMycobacterium tuberculosis
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Corynebacteriales
Family : Mycobacteriaceae
Genus : Mycobacterium
Species : tuberculosis
Strain : H37Rv
Taxonomic ID (NCBI) 83332
Genome Information
GenBank NC_000962.3
Organism Additional Information It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens.
Gene Information
Gene NameRv2873
Protein Information
Protein NameMpt83
NCBI RefSeq AF189006_1
UniProtKB Sequence >AAF13400.1 Mpt83, partial [Mycobacterium tuberculosis H37Rv] DTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ
Function Cell wall and cell processes
Glycosylation Status
Glycosylation Type O- (Ser) linked
Experimentally Predicted Glycosites S50
Experimentally Validated Glycosite(s) in Full Length ProteinS50
Experimentally Validated Glycosite(s ) in Mature Protein>AAF13400.1 Mpt83, partial [Mycobacterium tuberculosis H37Rv] DTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQAS*(50)PSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ
Glycosite(s) Annotated Protein Sequence LTYHVIAGQASPSRIDGTHQT
Technique(s) used for Glycosylation DetectionLC-MS/MS analysis
Glycan Information
Glycan Annotation Mannose
Technique(s) used for Glycan Identification nano LC-MS/MS analysis
Literature
Year of Identification2020
ReferenceTucci, P., Portela, M., Chetto, C.R., González-Sapienza, G. and Marín, M., 2020. Integrative proteomic and glycoproteomic profiling of Mycobacterium tuberculosis culture filtrate. PloS one, 15(3), p.e0221837.
Corresponding Author Paula Tucci
ContactBiochemistry Section, Faculty of Sciences, University of the Republic, Montevideo, Uruguay.