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S.No ProGT/ ProGP ID GT/GP name Organism Name GT family Patent Number PCT No CPC Classification No Priority date Date of publication Legal Status
Title : Conjugate vaccine against gram-negative bacterial infections
Inventors : Castric Peter, Cross Alan S, Sadoff Jerald C
1 ProGT1 (PilO) PilO Pseudomonas aeruginosa 1244 GTNC US 6872398 B2 G01N33/56911 22-12-1995 29-05-2005 Expired
Title : A Novel Pilin Glycoprotein From A Group 4 Pseudomonas Aeruginosa Strain
Inventors : Burrows Lori L , Kus Julianne V , Kelly John , Voisin Sebastien , Houliston Scott
2 ProGT26 (TfpW) TfpW Pseudomonas aeruginosa GTNC WO2007/128136A1 PCT/CA2007/000849 C07K14/21 09-05-2006 15-11-2005 Pending
Title : Glyocoproteins as well As vaccines, antibodies and antibody fragments useful for Combating campylobacter bacteria.
Inventors : Young Noel M, Brisson Jean-Robert , Kelly John F, Watson David C, Szymanski Christine M , Jarrell Harold C
3 ProGT10 (PglB) PglB Campylobacter jejuni NCTC 11168 GT66 US 20060165728A1 / US 7598354 B2 PCT/CA03/01156 G01N33/56922 01-08-2002 27-07-2006 Active
Title : o-glycosylated proteins
Inventors : Feldman Mario, Faridmoayer Amirreza
4 ProGT25(PglL) PglL Neisseria meningitidis MC58 WO 2008093165 A2/WO 2008093165 A2 PCT/IB2007/004486 C12P21/005 13-12-2006 07-08-2008 Pending
Title : Process for production of vaccines
Inventors : Reineke Jessica
5 ProGT5 (TcsL) TcsL Clostridium sordellii GT44 WO 2010/063693 A1 PCT/EP2009/066109 A61K39/08 03-12-2008 10-06-2010 Pending
Title : Glycoconjugation of polypeptides using oligosaccharyltransferases
Inventors : Defrees Shawn
6 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US20100286067A1 PCT/US09/30503 C12Y304/21022 08-01-2008 11-11-2010 Discontinued
Title : Bioconjugate vaccines.
Inventors : Wacker Michael, Kowarik Michael, Wetter Michael
7 ProGT10 (PglB) PglB Campylobacter jejuni NCTC 11168 GT66 US 20110274720A1 A61K39/085 06-05-2010 10-11-2011 Active
Title : Recombinant N-glycosylated bioconjugates
Inventors : Fernandez Fabiana, Wetter Michael, Kowarik Michael, Wacker Michael
8 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US20110097357A1 PCT/IB2009/000287 A61K39/0283 20-02-2008 28-04-2011 Active
Title : Acinetobacter O-oligosaccharyltransferases And Uses Thereof
Inventors : Feldman Mario, Nasr Mohamed Adel
9 ProGT84 (PglLComP) PglLComP Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) US 2018/0050101 A1/ WO2016134485A1 PCT/CA2016/050208 A61K39/09 26-02-2015 22-02-2011 Active
Title : Glycosylated Protein Expression In Prokaryotes
Inventors : Delisa Matthew, Guarino Cassandra, Mansell Thomas, Fisher Adam
10 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2011/0039729 A1 PCT/US09/30110 C12N15/70 03-01-2008 17-02-2011 Active
Title : Biosynthetic System That Produces Immunogenic Polysaccharides In Prokaryotic Cells
Inventors : Wacker Michael, Waechter Charles
11 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2013/0028926 A1 PCT/US10/02980 A61K39/0258 19-11-2009 31-01-2013 Active
Title : Bioconjugate vaccines made in prokaryotic cells
Inventors : Faridmoayer Amirreza
12 ProGT10 (PglB) PglB Campylobacter jejuni GT66 EP 2753353 A1 PCT/EP2012/067460 C07K14/22 06-09-2011 16-07-2014 Discontinued
Title : Pasteurellaceae vaccines
Inventors : Aebi Markus, Schwarz Flavio, Naegeli Andreas
13 ProGT42 (ApNGT) NGT Actinobacillus pleuropneumoniae GT41 US 2014/0194346 A1 PCT/EP2012/065480 C07K14/285 08-08-2011 10-07-2014 Discontinued
Title : Engineered oligosaccharyltransferases
Inventors : Ollis Anne A, Fisher Adam C, Merritt Judith H, Delisa Matthew P
14 ProGT10 (PglB) PglB Campylobacter jejuni GT66 WO2016023018A2 PCT/US2015/044395 C12Y204/01 08-08-2014 11-02-2016 Pending
Title : ApNGT gene of actinobacillus pleuropneumoniae and application of ApNGT gene
Inventors : Cheng Jiansong, Song Qitao, Wang Peng
15 ProGT42 (ApNGT) ApNGT Actinobacillus pleuropneumoniae GT41 CN105505959A C07K1/1077 11-01-2016 20-04-2016 Discontinued
Title : N-glycosylation of peptides and proteins
Inventors : Davis Benjamin G, Vijayakrishnan Balakumar, Lui Feng, Wacker Michael, Faridmoayer Amirreza, Kowarik Michael Thomas
16 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2016/0257983 A1 PCT/GB2014/053099 C12P19/18 16-10-2013 08-09-2016 Discontinued
Title : Relaxed acceptor-site specificity
Inventors : Aebi Markus, Locher Kaspar, Lizak Christian
17 ProGT47 (ClPglB) PglB Campylobacter lari ATCC BAA-1060D GT66 EP 2705155 B1 PCT/EP2012/001902 G06F19/16 04-05-2011 27-04-2016 Active
Title : Recombinant N-glycosylated proteins from procaryotic cells
Inventors : Aebi Markus, Kowarik Michael, Ahuja Umesh
18 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US9551019 B2 PCT/EP2006/004397 C12P21/005 11-05-2005 24-01-2017 Active
Title : Immunogenic Composition
Inventors : Faridmoayer Amirreza, Gerber Sabina Marietta
19 ProGT10 (PglB) PglB Campylobacter jejuni GT66 WO 2017/216286 A1 PCT/EP2017/064659 A61K39/092 17-06-2016 21-12-2017 Pending
Title : N glycosyl transferase AaNGT and application thereof
Inventors : Chen Min, Kong Yun, Li Jiang
20 ProGT122 (AaNGT) AaNGT Aggregatibacter aphrophilus GT41 CN107034202A C07K1/1077 26-06-2017 11-08-2017 Discontinued
Title : A multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof
Inventors : Rao Alka, Nagar Rupa
21 ProGT116 (EntS) EntS Enterococcus fecalis GT2 WO 2017/175239 A1 PCT/IN2017/050116 C12N9/1051 05-04-2016 17-10-2017 Pending
Title : Methods of producing glycosylated proteins
Inventors : Wetter Michael L, Kowarik Michael T, Faridmoayer Amirreza, Mally Manuela, Lizak Christian A, Aebi Markus, Lin Chia-Wei, Hang Ivan, Keys Timothy
22 ProGT42 (ApNGT) ApNGT Actinobacillus pleuropneumoniae GT41 WO 2017/093291 A1 PCT/EP2016/079332 C12P19/04 30-11-2015 08-06-2017 Pending
Title : Method For Preparing Bacterial Polysaccharide-modified Recombinant Fusion Protein And Use Of The Protein
Inventors : Wu Jun, Pan Chao, Sun Peng, Wang Hengliang, Liu Bo, Peng Zhehui, Zhu Li, Chang Shaohong, Gong Xin, Feng Erling, Wang Bin, Zeng Ming
23 ProGT17 (PglL) PglL Neisseria meningitidis US 2018/0258145 A1 PCT/CN2015/088737 C07K14/33 27-11-2014 13-09-2018 Active
Title : Oligosaccharide Compositions, Glycoproteins And Methods To Produce The Same In Prokaryotes
Inventors : Fisher Adam C, Merritt Judith H, Hamilton Brian S, Valderrama-Rincon Juan D, Delisa Matthew P
24 ProGT10 (PglB) PglB Campylobacter jejuni GT66 EP 2971030 B1 PCT/US2014/026990 C12P19/04 14-03-2013 17-10-2018 Active
Title : Method of diagnosing bacterial infections using bacterial glycoproteins
Inventors : Feldman Mario, Iwashkiw Jeremy, Ugalde Juan Esteban, Ciocchini Andres Eduardo, Comerci Diego Jose
25 WO 2013/023296 A1 PCT/CA2012/050549 G01N 33/564 12-08-2011 19-12-2018 Pending
Title : Production of recombinant vaccine in E. coli by enzymatic conjugation
Inventors : Wacker Michael, Kowarik Michael , Wetter Michael, Faridmoayer Amirreza
26 WO 2014/072405 A1 PCT/EP2013/073266 C12N 15/70, A61K 39/09 07-11-2012 19-12-2018 Pending
Title : Glycosylation Method
Inventors : Wren Brendan, Cuccui Jon, Abouelhadid Sherif
27 WO 2014/111724 A1 PCT/GB2014/050133 C12N 9/10, C12P 21/00, C12N 15,63, A61K 47/61, A61K 39/02 18-01-2013 29-08-2018 Pending
Title : Method for rapid in vitro synthesis of bioconjugate vaccines via recombinant production of n-glycosylated proteins in prokaryotic cell lysates
Inventors : Jewett Michael Christopher, Stark Jessica Carol, Delisa Matthew P, Jaroentomeechai Thapakorn
28 OST US20180016612A1 C12P 21/02, C12R 1/145, C12N 9/10 14-07-2016 18-01-2018 Active
Title : Cell-free glycoproteins synthesis (Cfgps) in prokaryotic cell lysates enriched with components for glycosylation
Inventors : Jewett Michael Christopher, Stark Jessica Carol, Delisa Matthew P, Jaroentomeechai Thapakorn
29 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2018/0298416 A1 C12P 21/00, C07K 14/47, C12N 15/52, C12N 1/20, C12P 19/18, C12N 15/62 30-12-2015 18-10-2018 Active
Title : Design of protein glycosylation sites by rappid expression and characterization of N-glycosyltransferases
Inventors : Jewett Michael, Kightlinger Weston, Lin Liang, Mrksich Milan
30 NGT WO 2019/035916 A1 PCT/US2018/000185 15-07-2017 21-02-2019 Pending
Title : Bioconjugates made from recombinant N-glycosylated proteins from procaryotic cells
Inventors : Fernandez Fabiana, Wetter Michael, Kowarik Michael, Wacker Michael
31 EP 3427749 A1 A61K 39/02, A61K 39/385, A61K 39/00, A61K 39/108, A61K 39/112, A61K 39/104, C07K 14/195 20-02-2008 16-01-2019 Pending
Title : Compositions and methods for protein glycosylation
Inventors : Haas Jurgen, Ihssen Julian, Kowarik Michael Thomas, Schwede Torsten Franz, Thöny-Meyer Linda Christiane
32 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2019/0078064 A1 PCT/EP2015/081229 C12N 9/10, C12P 21/00 30-12-2014 14-03-2019 Active
Title : Compositions and methods fro rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates
Inventors : Jewett Michael Christopher, Stark Jessica Carol, Delisa Matthew P, Jaroentomeechai Thapakorn
33 ProGT10 (PglB) PglB Campylobacter jejuni GT66 US 2019/0284600 A1 C12P 21/00, A61K 39/108, C12N 9/10 19-05-2018 19-09-2019 Active
Title : Modular platform for producing glycoproteins and identifying glycosylation pathways
Inventors : Jewett Michael C, Kightlinger Weston K
34 NGT (ApNGT, EcNGT, HiNGT, MhNGT, HdNGT, BtNGT, AaN Actinobacillus pleuropneumoniae, Escherichia coli, Haemophilus influenza, Mannheimia haemolytica, Haemophilus dureyi, Bibersteinia trehalosi, Aggregatibacter aphrophilus, Yersinia enterocolitica, Yersinia pestis, Kingella kingae WO2020/167455 PCT/US2020/0 15242 C12N 15/56, C12N 9/48, C12N 15/57, A61K, 38/14 27-01-2020 20-08-2020 Pending
Title : Bioconjugate vaccines' synthesis in prokaryotic cell lysates
Inventors : Jewett Michael, Stark Jessica, Delisa Matthew, Jaroentomeechai Thapakorn
35 OST C jejuni, Franciscella tularensis, Escherichia coli, Haemophilus influenzae, Neisseria meningitidis, Corynebacterium diphtheriae, Clostridium tetani WO 2020/146814 A1 PCT/US2020/0 13207 C12P 21/02, CP12P 19/18 11-01-2019 16-07-2020 Pending
Title : O-linked glycosylation recognition motifs
Inventors : Harding Christian
36 PglS, ComP glycosylation tag WO 2020/131236 PCT/US20 19/159893 A61K 38/02, A61K 48/00, A61K 39/02, C07K 14/195 21-12-2018 25-06-2020 Pending
Title : Recombinant microbial system for directed evolution of glycocins and a method of preparation thereof
Inventors : Rao Alka, Choudhary Pravinkumar Vishavanath
37 EntS, SunS, GccA WO 2020/044371 A1 PCT/IN20 19/050623 C12N 15/09 29-08-2018 05-03-2020 Pending
Title : Oligosaccharyltransferase polypeptide
Inventors : Cuccui Jon, Wren Brendan
38 US 2020/0032226 A1 PCT/GB2018/050647 C12N 9/10, C12P 21/00, C12N 15/74 15-03-2017 30-01-2020 Active
Title : Methods and compositions for making bacteriocins and antimicrobail peptides
Inventors : Gabant Philippe
39 US 2020/0263221 A1 PCT/US2018/048846 C12P 21/02, B01L 3/00, C07K 14/195 31-08-2017 20-08-2020 Active
Title : Modified campylobacter jejuni glycosyltransferase as well as preparation method and application thereof
Inventors : Su Yanting, Deng Mengxue, Yang Xiuyi, Zhu He, Li Zhunjie, Liu Wu
40 Cgt1 Campylobacter jejuni CN 113652410 A C12N9/1051 14-09-2021 16-11-2021 Pending
Title : Bacterial system for producing human O-glycoproteins
Inventors : Delisa Matthew, Natarajan Aravind
41 Gne, PglC, PglL, PglO C. jejuni, Acinetobacter haumannii ATCC 17978, Neisseria meningitides, Neisseria gonorrhoeae WO 2021/217037 A2 PCT/US2021/028901 Not classified 23-04-2020 28-10-2021 Pending
Title : Compositions and methods fro sialylated mucin-type O-glycoyslation of therapeutic proteins
Inventors : Withers Stephen G, Simm Lyann, Wakarchuk Warren William
42 CgtB C. jejuni WO 2021/081670 A1 PCT/CA2020/051480 C12N 15/63, C12N 15/74, C12N 1/21, C12N 9/10, C12N 15/54, C12N 9/90, C12N15/61, C12P 21/00 01-11-2019 06-05-2021 Pending
Title : Mutated PglB oligosaccharyl transferase enzymes
Inventors : Ihnken Leigh Anne, Karpiak Joel, Kemmler Stefan Jochen, Kowarik Michael Thomas, Melby Joel, Ollis Anne, Quebatte Julien Laurent
43 ProGT10 (PglB) PglB Campylobacter jejuni GT66 WO 2021/028303 A1 PCT/EP2020/072102 C12N 9/10, C12P 21/00 09/08/2019
06/11/2019		 18-02-2021 Pending
Title : Quantification of bioconjugate glycosylation
Inventors : Biagini Massimiliano, Fontana Lucia Eleonora, Galea Anna, Norais Nathalie, Scarselli Maria
44 WO 2021/013854 A1 PCT/EP2020/070595 C12P21/00, C12Q 1/37, C07K 14/31, C07K 14/205, C07K 14/21, C07K14/22, C07K14/245, C07K14/33, A61K 39/085, A61K 39/02, G01N 33/68, A61K 39/00, A61K39/385 23-07-2019 28-01-2021 Pending
Title : Compositions and methods relating to a mutant Clostridium difficile toxin
Inventors : Lotvin Jason Arnold, Anderson Annaliesa Sybil, Donald Robert G K, Flint Michael James, Kalyan Narender Kumar, Jansen Kathrin Ute , Sidhu Maninder K, Moran Justin Keith, Ruppen Mark Edward, Sun Weiqiang
45 US 2021/0024903 A1 C12N 9/10, C07K 14/33, C12N 1/20 21-10-2012 28-01-2021 Pending
Title : Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates
Inventors : Jewett Michael Christopher, Stark Jessica Carol, Hershewe Jasmine
46 OST US 2021/0147894 A1 PCT/US2019/027733 C12P 21/00, C12N 9/02, C12N 9/10, C12N 9/16, C12N 9/88, C12N 9/00, C12N 1/20 16-04-2018 20-05-2021 Pending
Title : FlmG-dependent soluble protien O-glycosylation systems in bacteria
Inventors : Viollier Patrick, Ardissone Silvia, Kint Nicolas
47 FlmG Caulobacter crescentus WO 2022/079220 A2 PCT/EP2021/078565 C12N15/52 15-10-2020 21-04-2022 Pending
Title : Engineered N-Glycosyltransferases with altered specificities
Inventors : Jewett Michael, Kightlinger Weston, Mrksich Milan, Lin Liang
48 NGT Actinobacillus pleuropneumoniae, Kingella spp., Haemophilus spp., Aggregatibacter spp. WO 2022/016188 A2 PCT/US2021/070878 C12N 9/10 14-07-2020 20-01-2022 Pending
Title : Glycosylated large S-layer protein and methods of use
Inventors : Mohamadzadeh Mansour, Ge Yong
49 LspA (S-layer) P. freudenreichii WO 2020/219736 A1 PCT/US2020/029602 C07K 14/195, C12Q 1/02, C12Q 1/04 26-04-2019 29-10-2022 Pending
Title : Klebsiella pneunomiae O-antigen glycosylated proeins and methods of making and uses thereof
Inventors : Harding Christian, Knoot Cory
50 PglS WO 2022/147142 PCT/US2021/065533 A61/K 47/65, A61K 39/385, A61K 38/00, A61K 47/64 31-12-2020 07-07-2022 Pending
Title : Minimal sequons sufficient for O-linking glycosylation
Inventors : Knoot Cory, Harding Christian
51 PglS WO 2022/232256 A1 PCT/US2022/026517 A61K 39/2, A61P 31/04, A61K 47/64, A61P 37/04 28-04-2021 03-11-2022 Pending

Source: lens.org & Google Patents