ProGP15 (N-acetylmuramoylhydrolase (Muramidase-2))
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| ProGP ID | ProGP15 (N-acetylmuramoylhydrolase (Muramidase-2)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Enterococcus hirae (Streptococcus faecium ATCC 9790) |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Enterococcaceae Genus : Enterococcus Species : hirae Strain : ATCC 9790 |
| Taxonomic ID (NCBI) | 1354 |
| Genome Information | |
| GenBank | M77639 |
| EMBL | M77639 |
| Protein Information | |
| Protein Name | N-acetylmuramoylhydrolase (Muramidase-2) |
| UniProtKB/SwissProt ID | P39046 |
| EMBL-CDS | AAA24776.1 |
| UniProtKB Sequence | >sp|P39046|MUR2_ENTHR Muramidase-2 OS=Enterococcus hirae PE=1 SV=1 MENIARKERRRLNETKRFRKVKRSAALVGTAMVGCSVAAPLIQPVQVDADQTPTQFGARI NTAAFIAEIATYAQPIAQANDLYASVMIAQAVVESGWGSSALSQAPYYNLFGIKGSYQGQ TVYMDTLEYLNNKWVSKKEPFRQYPSFAESFNDNAYVLRNTSFGNGYYYAGTWKSNTKSY TDATACLTGRYATDPGYAGKLNNIITTYGLTKYDTPASGNAGGGVTIGNGGNTGNTSNSG STSGNSGGSATTTGTTYTVKSGDSVWGISHSFGITMAQLIEWNNIKNNFIYPGQKLTIKG GQSAGSSTTNTGNNASSGNTSGNTNTSGSTGQATGAKYTVKSGDSVWKIANDHGISMNQL IEWNNIKNNFVYPGQQLVVSKGSSSASGSTSNTSTGNTSSNTANTGSTTSGSTYTVKAGE SVWSVSNKFGISMNQLIQWNNIKNNFIYPGQKLIVKGGSSSSNASTSTANNKNTASSNTS STATGQATYTVKAGESVWGVANKNGISMNQLIEWNNIKNNFIYPGQKLIVKGGSSKASAT ATIKPTASTPASTTPTASSTGDTKYTVKAGESVWGVANKHHITMDQLIEWNNIKNNFIYP GQEVIVKKGTAQSTPAKSDEKTYTVKAGESVWGVADSHGITMNQLIEWNNIKNNFIYPGQ QLIVKK |
| Sequence length | 666 AA |
| Subcellular Location | Secreted |
| Function | It has an endogenous, autolytic peptidoglycan hydrolase activity with a single specificity that is β-1,4-N-acetylmuramoylhydrolase (muramidase; EC 3.2.1.17). |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Periodic acid-Schiff (PAS) staining and binding to concanavalin A-Sepharose 4B column |
| Glycan Information | |
| Glycan Annotation | Glucose monomers and glucose oligosaccharides. |
| Literature | |
| Year of Identification | 1983 |
| Year of Identification Month Wise | 1983.1 |
| Reference | Kawamura, T. and Shockman, G.D., 1983. Purification and some properties of the endogenous, autolytic N-acetylmuramoylhydrolase of Streptococcus faecium, a bacterial glycoenzyme. Journal of Biological Chemistry, 258(15), pp.9514-9521. |
| Corresponding Author | G D Shockman |
| Contact | From the Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania |
