ProGP174 (Flagellin A)
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| ProGP ID | ProGP174 (Flagellin A) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Helicobacter felis CS1 |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Epsilonproteobacteria Orders : Campylobacterales Family : Helicobacteraceae Genus : Helicobacter Species : felis Strain : CS1 |
| Taxonomic ID (NCBI) | 936155 |
| Genome Information | |
| GenBank | FQ670179.2 |
| EMBL | FQ670179 |
| Gene Information | |
| Gene Name | flaA (Hfelis_04060) |
| NCBI Gene ID | 10050848 |
| GenBank Gene Sequence | NC_014810.2 |
| Protein Information | |
| Protein Name | Flagellin A |
| UniProtKB/SwissProt ID | Q9XB38 |
| NCBI RefSeq | WP_013468860.1 |
| EMBL-CDS | CBY82490.1 |
| UniProtKB Sequence | >sp|Q9XB38|FLAA_HELFC Flagellin A OS=Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1) GN=flaA PE=3 SV=3 MAFQVNTNINALNAHAMGLVTQRELKESLERLSSGLRINKAADDASGMTIADSLRSQAKS LGQAIANTNDGMGIIQIADKAMDEQIKILDTIKVKATQAAQDGQNTQSRKALQADIVRLI QSLDNIGNTTSYNGQTLLSGAFSNKEFQVGAYSNETIKASIGSATSDKIGQVKITTGKNI TASGEVALTFKQVDGVHDVSLESVKISTSAGTGLGVLAEVINKNSNATGVRATANVITTS DSAIKSGSLSSLTVNGIEIGNILGIKKNDSDGRLVAALNAVTAQTGVEAYTDSVGRLNLR SIDGRGINIKANSTNVDGQASALTTLNGGQDITRGSTNFGRLSLVRQDARDILVVSGANV SASAGYAAIGFAKGTTANTTVNLRDVLGEFNQAVRSASGANYNKTLASENLTLGSGVTTL RGAMVVMDIAESAQKMLDKVRSDLGSVQNQMVSTVNNITITQVNVKAAESQIRDVDFAQE SANFSKNNILAQSGSYAMSQANTVQQNILRLLT |
| Sequence length | 513 AA |
| Subcellular Location | Secreted |
| Function | FlaA and FlaB are co-assembled into one flagellar flament. H. felis flaA mutants possess truncated sheathed flagella and are unable to colonize murine stomach. |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | DIG (digoxigenin)-tagged hydrazine labeling after periodate treatment. |
| Literature | |
| Year of Identification | 1999 |
| Year of Identification Month Wise | 1999.7 |
| Reference | Josenhans, C., Ferrero, R.L., Labigne, A. and Suerbaum, S., 1999. Cloning and allelic exchange mutagenesis of two flagellin genes of Helicobacter felis. Molecular microbiology, 33(2), pp.350-362. |
| Corresponding Author | Sebastian Suerbaum |
| Contact | Ruhr University Bochum, Department of Medical Microbiology, D-44780 Bochum, Germany. |