ProGP285 (PpiB)
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| ProGP ID | ProGP285 (PpiB) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium tuberculosis |
| Domain | Bacteria |
| Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
| Taxonomic ID (NCBI) | 1773 |
| Genome Information | |
| GenBank | AL123456.3 |
| EMBL | BX842580 |
| Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
| Gene Information | |
| Gene Name | ppiB (Rv2582) |
| NCBI Gene ID | 887691 |
| GenBank Gene Sequence | NC_000962.3 |
| Protein Information | |
| Protein Name | PpiB |
| UniProtKB/SwissProt ID | P9WHW1 |
| NCBI RefSeq | NP_217098.1 |
| EMBL-CDS | AL123456.3 |
| UniProtKB Sequence | >sp|P9WHW0|PPIB_MYCTO Probable peptidyl-prolyl cis-trans isomerase B OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=ppiB PE=3 SV=1 MGHLTPVAAPRLACAFVPTNAQRRATAKRKLERQLERRAKQAKRRRILTIVGGSLAAVAV IVAVVVTVVVNKDDHQSTTSATPTDSASTSPPQAATAPPLPPFKPSANLGANCQYPPSPD KAVKPVKLPRTGKVPTDPAQVSVSMVTNQGNIGLMLANNESPCTVNSFVSLAQQGFFKGT TCHRLTTSPMLAVLQCGDPKGDGTGGPGYQFANEYPTDQYSANDPKLNEPVIYPRGTLAM ANAGPNTNSSQFFMVYRDSKLPPQYTVFGTIQADGLTTLDKIAKAGVAGGGEDGKPATEV TITSVLLD |
| Sequence length | 308 AA |
| Function | Probable peptidyl-prolyl cis-trans isomerase B (EC=5.2.1.8). It may be involved in protein folding. |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
| Literature | |
| Year of Identification | 2009 |
| Year of Identification Month Wise | 2009.2 |
| Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
| Corresponding Author | Clara Espitia |
| Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |