ProGP286 (PstS2)
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| ProGP ID | ProGP286 (PstS2) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium tuberculosis |
| Domain | Bacteria |
| Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
| Taxonomic ID (NCBI) | 1773 |
| Genome Information | |
| GenBank | AL123456.3 |
| EMBL | BX842575 |
| Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
| Gene Information | |
| Gene Name | pstS2 (Rv0932c) |
| NCBI Gene ID | 885613 |
| GenBank Gene Sequence | NC_000962.3 |
| Protein Information | |
| Protein Name | PstS2 |
| UniProtKB/SwissProt ID | P9WGT9 |
| NCBI RefSeq | WP_003898652.1 |
| EMBL-CDS | AL123456.3 |
| UniProtKB Sequence | >sp|P9WGT9|PSTS2_MYCTU Phosphate-binding protein PstS 2 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=pstS2 PE=1 SV=1 MKFARSGAAVSLLAAGTLVLTACGGGTNSSSSGAGGTSGSVHCGGKKELHSSGSTAQENA MEQFVYAYVRSCPGYTLDYNANGSGAGVTQFLNNETDFAGSDVPLNPSTGQPDRSAERCG SPAWDLPTVFGPIAITYNIKGVSTLNLDGPTTAKIFNGTITVWNDPQIQALNSGTDLPPT PISVIFRSDKSGTSDNFQKYLDGASNGAWGKGASETFNGGVGVGASGNNGTSALLQTTDG SITYNEWSFAVGKQLNMAQIITSAGPDPVAITTESVGKTIAGAKIMGQGNDLVLDTSSFY RPTQPGSYPIVLATYEIVCSKYPDATTGTAVRAFMQAAIGPGQEGLDQYGSIPLPKSFQA KLAAAVNAIS |
| Sequence length | 370 AA |
| Subcellular Location | Membrane |
| Function | Phosphate-binding lipoprotein PSTS2 (PBP-2) (PSTS2). Part of the ABC transporter complex pstSACB involved in phosphate import. It is induced by phosphate starvation. |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
| Literature | |
| Year of Identification | 2009 |
| Year of Identification Month Wise | 2009.2 |
| Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
| Corresponding Author | Clara Espitia |
| Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |