ProGP316 (Srr1)

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ProGP ID ProGP316 (Srr1)
Validation Status Uncharacterized
Organism Information
Organism NameStreptococcus agalactiae
Domain Bacteria
Classification Phylum : Firmicutes
Class : Bacilli
Orders : Lactobacillales
Family : Streptococcaceae
Genus : Streptococcus
Species : agalactiae
Taxonomic ID (NCBI) 211110
Genome Information
GenBank NC_004368.1
EMBL AL766851
Protein Information
Protein NameSrr1
UniProtKB/SwissProt ID Q8E473
EMBL-CDSCAD47188.1
UniProtKB Sequence >tr|Q8E473|Q8E473_STRA3 Uncharacterized protein OS=Streptococcus agalactiae serotype III (strain NEM316) GN=gbs1529 PE=1 SV=1 MSQKTFGKQLTVVDTKSRVKMHKSGKNWVRTVMSHFNLFKAIKGRATVEADVCIQDVEKE DRLSSGNLTYLKGILAAGALVGGASLTSRVYADETPVVQEQSSSVPTLAEQTEVTVKTTT VQNHQDGTVSKNIIDSNSVSMSESASTSTSESVSMSMSGSTLTSVSESVSTSALTSASES ISTSASESVSKSTSISEVSNILETQASLTDKGRESFSANQIVTESSLVTDAGKNASVSSL IEITKPKSELQTSKMSNESLITPEKSQVMIASDKTGNESLTPTIRLKSVIQPRSMNLMTL SSEMDLIPLEEVSDTEMLGKDVSSELQKVNIALKDNTLSEPGTVKLDSSENLVLNFAFSI ASVNEGDVFTVKLSDNLDTQGIGTILKVQDIMDETGQLLATGSYSPLTHNITYTWTRYAS TLNNIKARVNMPVWPDQRIISKTTSDKQCFTATLNNQVASIEERVQYNSPSVTEHTNVKT NVRSRIMKLDDERQTETYITQINPEGKEMYFASGLGNLYTIIGSDGTSGSPVNLLNAEVK ILKTNSKNLTDSMDQNYDSPEFEDVTSQYSYTNDGSKITIDWKTNSISSTTSYVVLVKIP KQSGVLYSTVSDINQTYGSKYSYGHTNISGDSDANAEIKLLSESASTSASTSASTSASMS ASTSASTSASMSASTSASTSASMSASTSASTSASTSTSTSASTSASTSASTSASMSASTS ASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASMS ASMSASTSASMSASTSASTSASTSASTSASTSASTSASMSASTSASTSASTSASMSASTS ASTSASTSASTSASTSTSTSASTSASTSASTSASMSASTSASTSPSTSASTSASTSASTS ASTSASTSASMSASTSASTSASMSASTSASTSASTSASTSASMSASTSASTSASTSASMS ASTSASTSASTSASTSASTSTSTSASTSASTSASTSASMSASTSASTSASTSASMSASTS ASISASTSASMSASTSASTSASTSASTSASMSASTSASTSASTSASTSASMSASTSASTS ASTSASTSASTSASTSASTSASTSSSTSASTSASTSASTSASMSASTSASTSASMSASTS ASTSASTSASMSASTSSSTSASMSASTSASMSASTSASTSASTSASMSASTSSSTSASMS ASTSASMSASTSASTSASTSASMSASTSASMSATTSASTSVSTSASTSASTSASTSSSSS VTSNSSKEKVYSALPSTGDQDYSVTATALGLGLMTGATLLGRKKSKKDKD
Sequence length 1310 AA
Subcellular LocationSurface
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Technique(s) used for Glycosylation DetectionLectin binding WITH Swga, Western blot analysis
Glycan Information
Glycan Annotation GlcNAc with hexose sugar
Protein Glycosylation linked (PGL) gene(s)
OST ProGT IDProGT33 ProGT34
Characterized Accessory Gene(s)gtfA and gtfB complex transfer GlcNAc ,with gtf(C-H) transfer hexose to GlcNac modified Srr1
Literature
Year of Identification2009
Year of Identification Month Wise2009.4.24
ReferenceMistou, M.Y., Dramsi, S., Brega, S., Poyart, C. and Trieu-Cuot, P., 2009. Molecular dissection of the secA2 locus of group B Streptococcus reveals that glycosylation of the Srr1 LPXTG protein is required for full virulence. Journal of bacteriology, 191(13), pp.4195-4206.
Corresponding Author Michel-Yves Mistou
ContactInstitut Pasteur, Unit of Biology of Gram-Positive Pathogenic Bacteria, URA CNRS 2172, Paris Cedex 15, France.
ReferenceChaze, T., Guillot, A., Valot, B., Langella, O., Chamot-Rooke, J., Di Guilmi, A.M., Trieu-Cuot, P., Dramsi, S. and Mistou, M.Y., 2014. O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry. Molecular & Cellular Proteomics, 13(9), pp.2168-2182.
Corresponding Author Trieu-Cuot P
ContactInstitut Pasteur, Unit of Biology of Gram-Positive Pathogenic Bacteria, URA CNRS 2172, Paris Cedex 15, France.