ProGP407 (EhaJ (autotranporter))

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ProGP ID ProGP407 (EhaJ (autotranporter))
Validation Status Uncharacterized
Organism Information
Organism NameEscherichia coli
Domain Bacteria
Classification Phylum : Proteobacteria
Class : gammaproteobacteria
Orders : Enterobacterales
Family : Enterobacteriaceae
Genus : Escherichia
Species : coli
Strain : B
Taxonomic ID (NCBI) 37762
Genome Information
GenBank CP014268.2
EMBL CP014268.2
Organism Additional Information Escherichia coli (Gram-negative) is the predominant facultative organism in the human intestine. It is responsible for a number of diseases like urinary tract infections, gastroenteritis (diarrhoea), meningitis, traveler's diarrhea and hemorrhagic colitis. There are a myriad of serotypes of pathogenic E. coli. Adhesion to the host cells is an important step in its pathogenesis. However, most strains are harmless and normal flora residing in the gut.
Gene Information
Gene NameehaJ
Protein Information
Protein NameEhaJ (autotransporter)
Subcellular LocationSurface
Function The glycosylated EhaJ has the ability to promote biofilm formation, adhesive properties mediate binding to various cellular and extracellular targets.
Glycosylation Status
Technique(s) used for Glycosylation DetectionDetection using glycoprotein specific Glycoprofile III stain
Literature
Year of Identification2011
Year of Identification Month Wise2011.6
ReferenceEaston, D.M., Totsika, M., Allsopp, L.P., Phan, M.D., Idris, A., Wurpel, D.J., Sherlock, O., Zhang, B., Venturini, C., Beatson, S.A. and Mahony, T.J., 2011. Characterization of EhaJ, a new autotransporter protein from enterohemorrhagic and enteropathogenic Escherichia coli. Frontiers in microbiology, 2, p.120.
Corresponding Author Mark A Schembri
ContactAustralian Infectious Disease Research Centre, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia