ProGP411 (FTL_1096)
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| ProGP ID | ProGP411 (FTL_1096) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Francisella tularensis ssp. holarctica strain LVS |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : gammaproteobacteria Orders : Thiotrichales Family : Francisellaceae Genus : Francisella Species : tularensis Subspecies : holarctica Strain : LVS |
| Taxonomic ID (NCBI) | 376619 |
| Genome Information | |
| GenBank | NC_007880.1 |
| EMBL | AM233362.1 |
| Organism Additional Information | Named LVS for live vaccine strain |
| Gene Information | |
| Gene Name | FTL_1096 |
| GenBank Gene Sequence | NC_007880.1 |
| Protein Information | |
| Protein Name | FTL_1096 |
| UniProtKB/SwissProt ID | Q19TM5 |
| NCBI RefSeq | WP_003019051.1 |
| EMBL-CDS | ABE26691.1 |
| UniProtKB Sequence | >tr|Q19TM5|Q19TM5_FRATU Conserved lipoprotein OS=Francisella tularensis subsp. holarctica GN=CH66_691 PE=4 SV=1 MTKKKLLKALAVAAIATSLVACSDSSSNDKTSTTAVSSGSSVATTTVAAPADNTNVTANA SYTIGYGMGSSIATDKNIKTFNFNNDKVMAGFEDAINAKKPAIPLEDIANNMNTLRDKMQ QQMNQKAVTSFLSVQDGIYNSDLTPKSDIKNPDVVVYEFFDYQCMYCSKLAPEIEKIMKD NSDVQVVFAEFPIFGQKLPASEYAAEVSTAIYKLYGADAYVKYHNGIFATGEDEGSLKNA TVDNVAKQAGADMTKVNKAIQDDKIADHLKDMLKMGFGQLGIQGAPFLVIAPAKNATVAN TTIIGGYTTADGIQAAINKAKSTATTTSTSNNGQTDTKHSQNDIATVTAEAQAISGSTEQ LAQQSQDDDSVEA |
| Sequence length | 373 AA |
| Subcellular Location | Periplasm |
| Function | DsbA homologue, involved in disulfide bond formation (through DsbA/DsbB system) |
| Protein Structure | |
| Protein Additional Information | DsbA homologue |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | Trypsin digestion and nLC-MS/MS |
| Glycan Information | |
| Glycan Annotation | Glycan has not been characterized but identified to be a hexasaccharide of 1156 Da |
| Literature | |
| Year of Identification | 2011 |
| Year of Identification Month Wise | 2011.11.1 |
| Reference | Thomas, R.M., Twine, S.M., Fulton, K.M., Tessier, L., Kilmury, S.L., Ding, W., Harmer, N., Michell, S.L., Oyston, P.C., Titball, R.W. and Prior, J.L., 2011. Glycosylation of DsbA in Francisella tularensis subsp. tularensis. Journal of bacteriology, 193(19), pp.5498-5509. |
| Corresponding Author | Richard W. Titball |
| Contact | College of Life and Environmental Sciences, University of Exeter, Exeter EX4 4QD, United Kingdom |