ProGP420 (FlaA (Polar flagellin))
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| ProGP ID | ProGP420 (FlaA (Polar flagellin)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Aeromonas hydrophila AH-3 (serotype O34) |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : gammaproteobacteria Orders : Aeromonadales Family : Aeromonadaceae Genus : Aeromonas Species : hydrophila Strain : AH-3 |
| Taxonomic ID (NCBI) | 644 |
| Genome Information | |
| GenBank | NZ_MTPO01000007.1. |
| EMBL | DQ860510 |
| Gene Information | |
| Gene Name | flaA |
| GenBank Gene Sequence | EU410314.1 |
| Protein Information | |
| Protein Name | FlaA (Polar flagellin) |
| UniProtKB/SwissProt ID | B3TZ62 |
| NCBI RefSeq | ACB38409.1 |
| EMBL-CDS | ACB38409.1 |
| UniProtKB Sequence | >tr|B3TZ62|B3TZ62_AERHY Flagellin OS=Aeromonas hydrophila subsp. hydrophila GN=flaA PE=3 SV=1 MGLYINTNVSSLNAQRNLMNTNKSLDTSYTRLASGLRINSAKDDAAGLQISNRLTSQING LDQGNRNANDGISVAQTAEGAMDEITSMLQRMRTLSQQSANGSNNTDDRTALQQEYTQLI TEIDRVAKDTTFGGTNILNGNYFGTFQVGADAGQTITFKLTSAFTLSGIASASKGSATVQ SVATADKYKVTKSATATTTTSVGSITTASAAQLAMANLDFMIKVVDSKRAELGAVQNRFD STIRNQANVSENVSAARSRIRDADFATETANLTKQNILQQAASTILSQANQRPQSALSLL QG |
| Sequence length | 302 AA |
| Subcellular Location | Flagellum |
| Function | FlaA is one of the two monomers of polar flagellin which is constitutively expressed. |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | Enzymatic Digests and Bottom Up Mass Spectrometry Analysis, Electrospray Liquid Chromatography Mass Spectrometry Analysis |
| Protein Glycosylation- Implication | O-Glycosylation is necessary for flagellar biogenesis. Pseudaminic acid biosynthetic genes pseB and pseF homologues, were found to be required for flagellar formation and flagellin expression. |
| Glycan Information | |
| Glycan Annotation | Heptasaccharide |
| Literature | |
| Year of Identification | 2012 |
| Year of Identification Month Wise | 2012.8.10 |
| Reference | Wilhelms, M., Fulton, K.M., Twine, S.M., Tomás, J.M. and Merino, S., 2012. Differential glycosylation of polar and lateral flagellins in Aeromonas hydrophila AH-3. Journal of Biological Chemistry, 287(33), pp.27851-27862. |
| Corresponding Author | Juan M. Tomás |
| Contact | Departamento de Microbiología, Facultad de Biología, Universidad de Barcelona, Diagonal 645, 08071 Barcelona, Spain. |