ProGP472 (Putative signal peptide)

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ProGP ID ProGP472 (Putative signal peptide)
Validation Status Characterized
Organism Information
Organism NameBurkholderia cenocepacia K56-2
Domain Bacteria
Classification Phylum : Proteobacteria
Class : Betaproteobacteria
Orders : Burkholderiales
Family : Burkholderiaceae
Genus : Burkholderia
Species : cenocepacia
Strain : K56
Taxonomic ID (NCBI) 985075
Genome Information
GenBank NZ_LAUA01000000
EMBL LAUA01000000
Organism Additional Information Burkholderia cenocepacia causes opportunistic infections in plants, insects, animals and humans. It acts as a health threat to cystic fibrosis patients, causing lethal necrotizing pneumonia in some cases.
Gene Information
Gene NameA0K9U9
GenBank Gene Sequence NC_011000.1
Protein Information
Protein NamePutative signal peptide
Sequence length 71 AA
Subcellular LocationPeriplasm
Function Putative signal peptide.
Glycosylation Status
Glycosylation Type O- (Ser/Thr) linked
Experimentally Validated Glycosite(s) in Full Length ProteinS35, S61 and S70
Technique(s) used for Glycosylation DetectionZIC-HILIC, immunoblotting, tryptic digestion, and MS/MS analysis
Technique(s) used for Glycosylated Residue(s) Detection MS/MS analysis
Glycan Information
Glycan Annotation Trisaccharide HexNAc-HexNAc-Hex.
BCSDB ID 12058
GlyTouCan G71937MV
Protein Glycosylation linked (PGL) gene(s)
OST Gene NamePglLBC
OST ProGT IDProGT71
Literature
Year of Identification2014
Year of Identification Month Wise2014.3.5
ReferenceLithgow, K.V., Scott, N.E., Iwashkiw, J.A., Thomson, E.L., Foster, L.J., Feldman, M.F. and Dennis, J.J., 2014. A general protein O‐glycosylation system within the B urkholderia cepacia complex is involved in motility and virulence. Molecular microbiology, 92(1), pp.116-137.
Corresponding Author Jonathan J. Dennis
ContactDepartment of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada,