ProGP549 (Pilin A6)

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ProGP ID ProGP549 (Pilin A6)
Validation Status Uncharacterized
Organism Information
Organism NameHaloferax volcanii H53
Domain Archaea
Classification Phylum : Euryarchaeota
Class : Halobacteria
Orders : Haloferacales
Family : Haloferacaceae
Genus : Haloferax
Species : volcanii
Strain : H53
Taxonomic ID (NCBI) 309800
Genome Information
GenBank CP001955.1
EMBL CP001955.1
Gene Information
Gene NamepilA6 (HVO_A0633)
NCBI Gene ID 8923526
GenBank Gene Sequence NC_013966.1
Protein Information
Protein NamePilin A6
UniProtKB/SwissProt ID D4GRU1
NCBI RefSeq WP_004040986.1
EMBL-CDSADE02056.1
UniProtKB Sequence >tr|D4GRU1|D4GRU1_HALVD Pilin PilA OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) OX=309800 GN=pilA6 PE=4 SV=1 MQIKTMFTESRAVSPVIGVILMVAITVILAAVIGTFVLGLGDQVGDTAPQASFTFDYDGT ELTITHESGAQIDGDLVTIAGDVNVTDSSDANKWSTLGSDTISAGESVVVQDTDEDGFAN GDTVRVVWTSESGSNSATLQRWTYNA
Sequence length 146 AA
Function Structural subunit of type IV pili involved in surface adhesion
Glycosylation Status
Glycosylation Type N- (Asn) linked
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Technique(s) used for Glycosylation DetectionAberrant migration on lithium dodecyl sulfate (LDS)-PAGE as detected through western blotting
Protein Glycosylation- Implication N-glycosylation may regulate the transition from planktonic cell to biofilm formation under stress conditions.
Protein Glycosylation linked (PGL) gene(s)
OST Gene NameAglB
Additional CommentPilin expression in pilA[1-6] aglB stimulates microcolony formation.
Literature
Year of Identification2016
Year of Identification Month Wise2016.05
ReferenceEsquivel, R.N., Schulze, S., Xu, R., Hippler, M. and Pohlschroder, M., 2016. Identification of Haloferax volcanii pilin N-glycans with diverse roles in pilus biosynthesis, adhesion, and microcolony formation. Journal of Biological Chemistry, 291(20), pp.10602-10614.
Corresponding Author Mechthild Pohlschroder
ContactFrom the Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104