ProGP727 (N-acetyl-gamma-glutamyl-phosphate reductase)
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| ProGP ID | ProGP727 (N-acetyl-gamma-glutamyl-phosphate reductase) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Ehrlichia ruminantium |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Alphaproteobacteria Orders : Rickettsiales Family : Anaplasmataceae Genus : Ehrlichia Species : ruminantium Strain : Gardel |
| Taxonomic ID (NCBI) | 302409 |
| Genome Information | |
| Organism Additional Information | Ehrlichia ruminantium is an obligate intracellular bacterium that causes heartwater, a fatal tick-borne disease of livestock |
| Gene Information | |
| Gene Name | argC |
| NCBI Gene ID | NC_006831.1 |
| Protein Information | |
| Protein Name | N-acetyl-gamma-glutamyl-phosphate reductase |
| UniProtKB/SwissProt ID | Q5FGD5 |
| UniProtKB Sequence | >sp|Q5FGD5|ARGC_EHRRG N-acetyl-gamma-glutamyl-phosphate reductase OS=Ehrlichia ruminantium (strain Gardel) OX=302409 GN=argC MSYQVSVAVVGATGYVGVELVRLLLFHPMVKIKYLCATQSIGSLLSSHYDHVLKDSIPVSISCFSSIDLSKVDVIFLCLPHGQSNEIVKKIHNEVKIIIDLSADFRIKDIDTYKEWYGAHCCPDLIQDFVYGLTEIYWEEIKKSRFVACPGCYATSALVPLFPLLRLRLVKSQNIIVDAKSGVSGAGRSVDQKKLFCEIHDVIKSYNISKHRHIPEIEQELCFAACQENINVQFVPNLIPVKRGMLSSIYLELEEGVSPIDIREALLVFYKDSKFIFIDEEKAITTKSVIGTNYCYIGVFPGRIPNTVIIVCNIDNLLKGASGQAVQNFNIMMSCDETTALLNIPYL |
| Subcellular Location | Cytosol |
| Function | Amino-acid biosynthesis |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | nLC–MS/MS Analysis |
| Literature | |
| Year of Identification | 2019 |
| Reference | Marcelino, I., Colomé-Calls, N., Holzmuller, P., Lisacek, F., Reynaud, Y., Canals, F. and Vachiéry, N., 2019. Sweet and sour ehrlichia: Glycoproteomics and phosphoproteomics reveal new players in Ehrlichia ruminantium physiology and pathogenesis. Frontiers in microbiology, 10, p.450. |
| Corresponding Author | Isabel Marcelino |
| Contact | 1. CIRAD, UMR ASTRE, Petit-Bourg, France. 2. ASTRE, CIRAD, INRA, Université de Montpellier, Montpellier, France. 3. Unitè TReD-Path (Transmission Rèservoirs et Diversitè des Pathogènes), Institut Pasteur de Guadeloupe, Les Abymes, France. |