ProGT119 (Maf)
| ProGT ID | ProGT119 (Maf) |
| Organism Information | |
| Organism Name | Magnetospirillum magneticum AMB-1 |
| Clinical Implication | Non-pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : AlphaProteobacteria Orders : Rhodospirillales Family : Rhodospirillaceaee Genus : Magnetospirillum Species : magneticum Strain : AMB-1 |
| Taxonomic ID (NCBI) | 342108 |
| Genome Information | |
| Gene Bank | AP007255 |
| EMBL | AP007255 |
| Gene Information | |
| Gene Name | amb0685 |
| Protein information | |
| Protein Name | Maf |
| UniProtKB/ SwissProt ID | Q2W9I6 |
| NCBI Ref Seq | WP_011383128.1? |
| UniProtKB Sequence | >tr|Q2W9I6|Q2W9I6_MAGSA Uncharacterized protein OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) OX=342108 GN=amb0685 PE=1 SV=1 MAAAPQINAELVSAYLEAFLELMPEMGERLRVHRPQSNLVVNEDGDLDVEFRGEFLYGPG GRKRIEDMATRTALGPDHRISAAPLSSGHVDLIVKRFLYNILKRATDSGLSFLQHPEESG GFHMVCLGLGLGYQLPILLEQDNPAGIHIVEPNFDFLYHSLSTVDWRPLLETRRENPLRL NIIIEEEPGQIARQLRSAIRCCCPIVVDWTRLFVAYNSPLLTAAMSEFMRDAQLIGIGLG FLHDEMEMTRASYKNMRDGRYSILQHSATQLHTPVFIVGSGPSIDDDIEVIKANQDRAVI ISCGTASRVLLANGIQPDFQMLLENGAAPYRALAAVHEEFGFGSATLIGSNTVDPRVRDL FEDVVYYFRPALSSYALFSPGIEYSLDDSGPTVTNTGTTAALALGFRELYLFGVDLGSRN PKRHHSKQSLYRHADDTKDGQKGAMDFDAVFDVREPGNFGGVVYSETIMLWTRDALGRII GRYRPAANAFNCSDGVMIENTRPLSSQSLRLKSTPDMKAKDLAKVRASFRPGGEELFHDR WDREDWPRSIVTLLGECAQAMDDHVGDSNRLMLVLSEMLLRDYKQPPTVAQFFVRGTLMM AAMCYDYYVKRVTPADRKAEFWEIIRDEFHQMIRVMTLQVEWYFDNIEAFESDEELFDKV TGWDYD |
| EMBL CDS | BAE49489.1 |
| Sequence length | 666 AA |
| Function in Native Organism | 1) Maf is involved in bacterial flagella glycosylation. |
| String | 342108.amb0685 |
| Potential Application | 1) 3D structure of Maf provides a structural template for the Maf family glycosyltransferases. 2) Structural studies may help the development of novel antibiotic agents specifically targeting these family pathogens. |
| Additional Information | 1) Maf dependent glycosylation of flagellin with pseudaminic acid is important for the assembly and export of flagellum monomers. |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser/Thr) linked |
| EC Number (BRENDA) | 2.4.1.- |
| Mechanism of Glycan Transfer | Sequential |
| Glycan Information | |
| Glycan transferred | A nonulosonic acids sugar (most likely pseudaminic acid) |
| Method of Glycan Indentification | LC-MS/MS |
| Experimental_strategies | In vivo |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Flagella |
| ProGPdb ID | ProGP682 |
| Litrature | |
| Year Of Validation | 2018 |
| Reference | Sulzenbacher, G., Roig?Zamboni, V., Lebrun, R., Guérardel, Y., Murat, D., Mansuelle, P., Yamakawa, N., Qian, X.X., Vincentelli, R., Bourne, Y. and Wu, L.F., 2018. Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation. Environmental microbiology, 20(1), pp.228-240. |
| Corresponding Author | International Associated Laboratory of Evolution and Development of Magnetotactic Organisms (LIA-MagMC), Centre National de la Recherche Scientifique, Marseille 13402, France. |