ProGT30 (Gap3)
| ProGT ID | ProGT30 (Gap3) |
| Organism Information | |
| Organism Name | Streptococcus parasanguinis FW213 |
| Clinical Implication | Pathogenic |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Streptococcaceae Genus : Streptococcus Species : parasanguinis Strain : FW213 |
| Taxonomic ID (NCBI) | 1114965 |
| Genome Information | |
| Gene Bank | CP003122.1 |
| EMBL | CP003122.1 |
| Gene Information | |
| Gene Name | gap3 |
| Protein information | |
| Protein Name | Gap3 |
| UniProtKB/ SwissProt ID | I1ZP95 |
| NCBI Ref Seq | WP_014713991.1 |
| UniProtKB Sequence | >tr|I1ZP95|I1ZP95_STRPA Glycosylation associated protein, mature Fap1 export and glycosylation,gap3 OS=Streptococcus parasanguinis FW213 GN=gap3 PE=4 SV=1 MTKQLISEIYWNEIRKGENYLYGSQIKFQEDLVNFYNPQLASGKPIVTFKSRTNYQGDRH SPDLPILIQGNRYLLEYQIDAVPANSFFLQLDFFNRQAEQIESIVLRNSGESFIFPKDTF TYTLTLMSAGCQSVTYQKFMIYDINDEEKKNHIVENRYLRELLPKDLDLVKNLIEYI |
| EMBL CDS | AFJ26869.1 |
| Sequence length | 177 AA |
| Additional Information | 1) The Gap1-Gap3 interaction is required for Fap1-dependent bacterial adhesion. |
| Glycosyltransferase Information | |
| Glycosylation Type | O- (Ser/Thr) linked |
| EC Number (BRENDA) | 2.4.1.- |
| Mechanism of Glycan Transfer | Sequential |
| Accessory GT ID | ProGT29.1,ProGT29.2 |
| Glycan Information | |
| Method of Glycan Indentification | GC-MS |
| Experimental_strategies | In vivo and In vitro |
| Acceptor Subtrate Information | |
| Acceptor Substrate name | Fap1 |
| ProGPdb ID | ProGP209 |
| Litrature | |
| Year Of Validation | 2008 |
| Reference | Li, Y., Chen, Y., Huang, X., Zhou, M., Wu, R., Dong, S., Pritchard, D.G., Fives?Taylor, P. and Wu, H., 2008. A conserved domain of previously unknown function in Gap1 mediates protein–protein interaction and is required for biogenesis of a serine?rich streptococcal adhesin. Molecular microbiology, 70(5), pp.1094-1104. |
| Corresponding Author | Department of Pediatric Dentistry, Schools of Dentistry and Medicine, University of Alabama, Birmingham, AL 35294, USA. |
| Reference | Zhou, M., Zhang, H., Zhu, F. and Wu, H., 2011. Canonical SecA associates with an accessory secretory protein complex involved in biogenesis of a streptococcal serine-rich repeat glycoprotein. Journal of bacteriology, 193(23), pp.6560-6566. |
| Corresponding Author | Department of Pediatric Dentistry, Schools of Dentistry and Medicine, University of Alabama, Birmingham, AL 35294, USA. |