ProGP1218 (SLP-5818)
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| ProGP ID | ProGP1218 (SLP-5818) |
| Validation Status | Characterized |
| Organism Information | |
| Organism Name | Lactobacillus kefiri JCM 5818 |
| Domain | Bacteria |
| Classification | Phylum : Firmicutes Class : Bacilli Orders : Lactobacillales Family : Lactobacillaceae Genus : Lactobacillus Species : kefiri Strain : JCM 5818 |
| Taxonomic ID (NCBI) | 1423764 |
| Gene Information | |
| Gene Name | aidA |
| Protein Information | |
| Protein Name | SLP-5818 |
| Subcellular Location | S-layer |
| Function | LPS-induced cell activation, immunostimulatory ability |
| Glycosylation Status | |
| Glycosylation Type | N- (Asn) linked |
| Experimentally Predicted Glycosites | N-55, N-457 |
| Experimentally Validated Glycosite(s) in Full Length Protein | N-55, N-457 |
| Glycan Information | |
| Glycan Annotation | (HexNAc)2-(Hex)3-(HexNAc)2-(Hex)2 |
| Technique(s) used for Glycan Identification | MALDI-TOF-MS analysis |
| Literature | |
| Year of Identification | 2020 |
| Reference | Malamud, M., Cavallero, G.J., Casabuono, A.C., Lepenies, B., de los Ángeles Serradell, M. and Couto, A.S., 2020. Immunostimulation by Lactobacillus kefiri S-layer proteins with distinct glycosylation patterns requires different lectin partners. Journal of Biological Chemistry, 295(42), pp.14430-14444. |
| Corresponding Author | María de Los Ángeles Serradell Alicia S Couto |
| Contact | Chair of Microbiology, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata, La Plata, Argentina University of Buenos Aires, Faculty of Exact and Natural Sciences, Department of Organic Chemistry-National Council for Scientific and Technical Research, Center for Research in Carbohydrates, Buenos Aires, Argentina |