ProGP123 (CRX (Copper response extracellular protein))
Home -> ProGPdb -> Search ProGP -> Display data
| ProGP ID | ProGP123 (CRX (Copper response extracellular protein)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Methanobacterium bryantii BKYH |
| Domain | Archaea |
| Classification | Family: Methanobacteriaceae Order: Methanobacteriales Class: Methanobacteria or Archaeobacteria Division or phylum: "Euryarchaeota" |
| Taxonomic ID (NCBI) | 2161 |
| Genome Information | |
| GenBank | U40213 |
| EMBL | U40213 |
| Gene Information | |
| Gene Name | crx |
| Protein Information | |
| Protein Name | CRX (Copper response extracellular protein) |
| UniProtKB/SwissProt ID | Q48929 |
| EMBL-CDS | AAA97868.1 |
| UniProtKB Sequence | >tr|Q48929|Q48929_METBR Copper response extracellular protein OS=Methanobacterium bryantii PE=4 SV=1 MVNIDKKIVIIVGIVILIAVVAGAFLVTGTASADNKVRVGYLPSTGDSLYFIAKEKGYFA DEGLDVQLNEFQTGPDEINSLLADKLDVEAGGVGEPLNFINNGKDLEIIGGAMGGGSSVI AKDNQTAQALRDKPKNYEGKTVATVKMSTPDVTIKAALKEQGVDLNKVNFVEFKTAADVV QAVKSGKAQVGLVWPPFEYTAQQQGLIIVKYSDEYQPNHPCCRIVTTETKLKANPDKWVK FERALIRAYDFYKNNPDETTAIVGKYVKMDQTTLKKALYNGHLSLVPDPNKKGTLAYWNF LEQLGYSNITNTSALDKSIDTTVYKTALDQLAQQNPNNANYKFLEKQYIKLDQ |
| Sequence length | 353 AA |
| Subcellular Location | Secreted |
| Function | The CRX proteins are secreted at higher levels by this methanogen in response to copper exposure. Likely to be involved in copper resistance, although they could be synthesized as part of a more generic stress response. N-terminal leader peptide, containing 28 AA, that is removed during extracellular secretion. |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | ConA binding and deglycosylation with neuraminidase. |
| Literature | |
| Year of Identification | 1995 |
| Year of Identification Month Wise | 1995.12 |
| Reference | Kim, B.K., Pihl, T.D., Reeve, J.N. and Daniels, L., 1995. Purification of the copper response extracellular proteins secreted by the copper-resistant methanogen Methanobacterium bryantii BKYH and cloning, sequencing, and transcription of the gene encoding these proteins. Journal of bacteriology, 177(24), pp.7178-7185. |
| Corresponding Author | Daniels, L. |
| Contact | Department of Microbiology, University of Iowa, Iowa City 52242, USA. |
| Reference | Kim, B.K., Pihl, T.D., Reeve, J.N. and Daniels, L. (1995) Purification of the copper response extracellular proteins secreted by the copper-resistant methanogen Methanobacterium bryantii BKYH and cloning, sequencing, and transcription of the gene encoding these proteins. J Bacteriol, 177, 7178-7185. [PubMed: 8522526] |
| Author | Daniels, L. |
| Research Group | Department of Microbiology, University of Iowa, Iowa City 52242, USA. |
| Corresponding Author | Kim, B.K., Pihl, T.D., Reeve, J.N. Daniels, L. |
| Contact | Department of Microbiology, University of Iowa, Iowa City 52242, USA. |