ProGP129 (RU 41740-P1 Glyoprotein fraction (non endotoxin))
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| ProGP ID | ProGP129 (RU 41740-P1 Glyoprotein fraction (non endotoxin)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Klebsiella pneumoniae |
| Domain | Bacteria |
| Classification | Phylum : Proteobacteria Class : Gammaproteobacteria Orders : Enterobacterales Family : Enterobacteriaceae Genus : Klebsiella Species : pneumoniae Subspecies : pneumoniae |
| Taxonomic ID (NCBI) | 272620 |
| Genome Information | |
| GenBank | NC_009648.1. |
| EMBL | CP000647 |
| Protein Information | |
| Protein Name | RU 41740- P1 Glyoprotein fraction (non endotoxin) |
| Subcellular Location | Intracellular |
| Function | Increases host resistance to various bacterial, viral, and fungal infections. Its protective effect can be linked to the functional activation of T cells, B cells, macrophages, natural killer cells, and polymorphonuclear neutrophils. RU 41740 improves cytokine production by murine macrophages and human leukocytes. |
| Literature | |
| Year of Identification | 1996 |
| Year of Identification Month Wise | 1996.8 |
| Reference | Guenounou, M., 1996. Mechanism of action of the immunomodulating agent RU 41740. Current therapeutic research, 57(13), pp.16-24. |
| Corresponding Author | Mancef Guenounou |
| Contact | Immunology Laboratory, University of Reims, Reims, France |