ProGP211 (TMBP (Trehalose/maltose binding protein)
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| ProGP ID | ProGP211 (TMBP (Trehalose/maltose binding protein) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Pyrococcus furiosus DSM 3638 |
| Domain | Archaea |
| Classification | Phylum : Euryarchaeota Class : Thermococci Orders : Thermococcales Family : Thermococcaceae Genus : Pyrococcus Species : furiosus Strain : DSM 3638 |
| Taxonomic ID (NCBI) | 2261 |
| Genome Information | |
| GenBank | AE009950.1 |
| EMBL | AE009950 |
| Gene Information | |
| Gene Name | malE (PF1739) |
| NCBI Gene ID | 1469617 |
| GenBank Gene Sequence | NC_003413 |
| Protein Information | |
| Protein Name | TMBP (Trehalose/maltose binding protein) |
| UniProtKB/SwissProt ID | O51923 |
| NCBI RefSeq | WP_011012883.1 |
| EMBL-CDS | AAL81863.1 |
| UniProtKB Sequence | >tr|O51923|O51923_PYRFU Trehalose/maltose binding protein OS=Pyrococcus furiosus GN=malE PE=1 SV=1 MNVKKVLLGLFLVGVLGIAVVASGCIGGQQTSTVTSTPTETSLQGKIVFAVGGAPNEIEY WKGVIAEFEKKYPGVTVELKRQATDTEQRRLDLVNALRGKSSDPDVFLMDVAWLGQFIAS GWLEPLDDYVQKDNYDLSVFFQSVINLADKQGGKLYALPVYIDAGLLYYRKDLLEKYGYS KPPETWQELVEMAQKIQSGERETNPNFWGFVWQGKQYEGLVCDFVEYVYSNGGSLGEFKD GKWVPTLNKPENVEALQFMVDLIHKYKISPPNTYTEMTEEPVRLMFQQGNAAFERNWPYA WGLHNADDSPVKGKVGVAPLPHFPGHKSAATLGGWHIGISKYSDNKALAWEFVKFVESYS VQKGFAMNLGWNPGRVDVYDDPAVVSKSPHLKELRAVFENAVPRPIVPYYPQLSEIIQKY VNSALAGKISPQEALDKAQKEAEELVKQYS |
| Sequence length | 450 AA |
| Subcellular Location | Membrane |
| Function | Binding protein-dependent ABC transporter mediating uptake of β-glucosides. It transports trehalose and maltose. |
| Protein Structure | |
| PDB ID | 1EUB |
| Glycosylation Status | |
| Glycosylation Type | N- (Asn) linked |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding, Periodic acid- Schiff reagent (PAS) staining. |
| Glycan Information | |
| Glycan Annotation | Glucose moieties. |
| Literature | |
| Year of Identification | 2002 |
| Year of Identification Month Wise | 2002.4 |
| Reference | Koning, S.M., Konings, W.N. and Driessen, A.J., 2002. Biochemical evidence for the presence of two α-glucoside ABC-transport systems in the hyperthermophilic archaeon Pyrococcus furiosus. Archaea, 1(1), pp.19-25. |
| Corresponding Author | Arnold J.M. Driessen |
| Contact | Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 90750 AA Haren, The Netherlands. |