ProGP245 (SraP (serine-rich adhesin for platelets)
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| ProGP ID | ProGP245 (SraP (serine-rich adhesin for platelets) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Staphylococcus aureus (ISP479C and PS767) |
| Domain | Bacteria |
| Classification | Family: Staphylococcaceae Order: Bacillales Class: Bacilli (or Firmibacteria) Division or phylum: "Firmicutes" |
| Taxonomic ID (NCBI) | 367830 |
| Genome Information | |
| GenBank | CP000255 |
| EMBL | CP000255 |
| Gene Information | |
| Gene Name | sraP |
| Protein Information | |
| Protein Name | SraP (serine-rich adhesin for platelets) |
| UniProtKB/SwissProt ID | Q2FUW1 |
| Sequence length | 2271 AA |
| Subcellular Location | Surface (Secreted) |
| Function | SraP, a cell wall-anchored glycoprotein, mediates the direct binding of S. aureus to platelets through a platelet-binding domain located within its N-terminal region. Its expression appears to be a virulence determinant in endovascular infection. |
| Glycosylation Status | |
| Glycosylation Type | O- (Ser/Thr) linked |
| Technique(s) used for Glycosylation Detection | Carbohydrate conntent analysis by glycan detection assay |
| Glycan Information | |
| Glycan Annotation | Glycosylated by GlcNAc-containing oligosaccharides in E. coli. |
| Protein Glycosylation linked (PGL) gene(s) | |
| OST ProGT ID | |
| Literature | |