ProGP245 (SraP (serine-rich adhesin for platelets)
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ProGP ID | ProGP245 (SraP (serine-rich adhesin for platelets) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Staphylococcus aureus (ISP479C and PS767) |
Domain | Bacteria |
Classification | Family: Staphylococcaceae Order: Bacillales Class: Bacilli (or Firmibacteria) Division or phylum: "Firmicutes" |
Taxonomic ID (NCBI) | 367830 |
Genome Information | |
GenBank | CP000255 |
EMBL | CP000255 |
Gene Information | |
Gene Name | sraP |
Protein Information | |
Protein Name | SraP (serine-rich adhesin for platelets) |
UniProtKB/SwissProt ID | Q2FUW1 |
Sequence length | 2271 AA |
Subcellular Location | Surface (Secreted) |
Function | SraP, a cell wall-anchored glycoprotein, mediates the direct binding of S. aureus to platelets through a platelet-binding domain located within its N-terminal region. Its expression appears to be a virulence determinant in endovascular infection. |
Glycosylation Status | |
Glycosylation Type | O- (Ser/Thr) linked |
Technique(s) used for Glycosylation Detection | Carbohydrate conntent analysis by glycan detection assay |
Glycan Information | |
Glycan Annotation | Glycosylated by GlcNAc-containing oligosaccharides in E. coli. |
Protein Glycosylation linked (PGL) gene(s) | |
OST ProGT ID | |
Literature |