ProGP253 (DgpC)
Home -> ProGPdb -> Search ProGP -> Display data
| ProGP ID | ProGP253 (DgpC) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Parabacteroides (Bacteroides) distasonis |
| Domain | Bacteria |
| Classification | Phylum : Bacteroidetes Class : Bacteroidia Orders : Bacteroidales Family : Tannerellaceae Genus : Parabacteroides Species : distasonis |
| Taxonomic ID (NCBI) | 823 |
| Genome Information | |
| GenBank | AB196154 |
| EMBL | AB196154 |
| Gene Information | |
| Gene Name | dgpC |
| Protein Information | |
| Protein Name | DgpC |
| Subcellular Location | Surface |
| Function | Most likely to be an S-layer glycoprotein as evidenced by its abundance, its similarity to known S-layers, its surface extraction and presence of an S-layer lattice on the organism. |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Pro-Q Emerald 300 Glycoprotein staining and AAL (Aleuria aurantia lectin) affinity chromatography |
| Glycan Information | |
| Glycan Annotation | Glycan represents 2.1% (wt/wt) of the molecule. It is composed almost entirely of xylose (89.6%). Glucose (6.9%), mannose (2.2%), and rhamnose (1.3%) are present in small amounts. 16 xylose residues and one or two glucose or other six-carbon sugar have been calculated per DgpC molecule. Glycosyl linkage analysis has shown that the xylose molecules are largely linked 1,2 and 1,4. |
| Protein Glycosylation linked (PGL) gene(s) | |
| Additional Comment | Expression of Dgp glycoproteins is phase-variable in the normal environment of bacteria. |
| Literature | |
| Year of Identification | 2007 |
| Year of Identification Month Wise | 2007.02 |
| Reference | Fletcher, C.M., Coyne, M.J., Bentley, D.L., Villa, O.F. and Comstock, L.E., 2007. Phase-variable expression of a family of glycoproteins imparts a dynamic surface to a symbiont in its human intestinal ecosystem. Proceedings of the National Academy of Sciences, 104(7), pp.2413-2418. |
| Corresponding Author | Laurie E. Comstock |
| Contact | Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. |