ProGP271 (FecB)
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ProGP ID | ProGP271 (FecB) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Mycobacterium tuberculosis |
Domain | Bacteria |
Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
Taxonomic ID (NCBI) | 1773 |
Genome Information | |
GenBank | AL123456.3 |
EMBL | BX842581 |
Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
Gene Information | |
Gene Name | fecB (Rv3044) |
NCBI Gene ID | 888745 |
GenBank Gene Sequence | NC_000962.3 |
Protein Information | |
Protein Name | FecB |
UniProtKB/SwissProt ID | O53291 |
NCBI RefSeq | NP_217560.1 |
EMBL-CDS | AL123456.3 |
UniProtKB Sequence | >tr|O53291|O53291_MYCTU PROBABLE FEIII-DICITRATE-BINDING PERIPLASMIC LIPOPROTEIN FECB OS=Mycobacterium tuberculosis GN=fecB PE=4 SV=1 MRSTVAVAVAAAVIAASSGCGSDQPAHKASQSMITPTTQIAGAGVLGNDRKPDESCARAA AAADPGPPTRPAHNAAGVSPEMVQVPAEAQRIVVLSGDQLDALCALGLQSRIVAAALPNS SSSQPSYLGTTVHDLPGVGTRSAPDLRAIAAAHPDLILGSQGLTPQLYPQLAAIAPTVFT AAPGADWENNLRGVGAATARIAAVDALITGFAEHATQVGTKHDATHFQASIVQLTANTMR VYGANNFPASVLSAVGVDRPPSQRFTDKAYIEIGTTAADLAKSPDFSAADADIVYLSCAS EAAAERAAVILDSDPWRKLSANRDNRVFVVNDQVWQTGEGMVAARGIVDDLRWVDAPIN |
Sequence length | 359 AA |
Subcellular Location | Periplasm |
Function | Probable FEIII-dicitrate-binding periplasmic lipoprotein. |
Glycosylation Status | |
Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
Literature | |
Year of Identification | 2009 |
Year of Identification Month Wise | 2009.2 |
Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
Corresponding Author | Clara Espitia |
Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |