ProGP273 (LppX (Putative lipoprotein))
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ProGP ID | ProGP273 (LppX (Putative lipoprotein)) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Mycobacterium tuberculosis |
Domain | Bacteria |
Classification | Family: Mycobacteriaceae Suborder: Corynebacterineae Order: Actinomycetales Subclass: Actinobacteridae Class: Actinobacteria Division or phylum: "Actinobacteria" |
Taxonomic ID (NCBI) | 1773 |
Genome Information | |
GenBank | BX842581.1 |
EMBL | BX842581 |
Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
Gene Information | |
Gene Name | lppX (Rv2945c) |
NCBI Gene ID | 887956 |
GenBank Gene Sequence | NC_000962.2 |
Protein Information | |
Protein Name | LppX (Putative lipoprotein) |
UniProtKB/SwissProt ID | P9WK65 |
NCBI RefSeq | WP_003414872.1 |
EMBL-CDS | CCP45749.1 |
UniProtKB Sequence | >sp|P9WK65|LPPX_MYCTU Putative phthiocerol dimycocerosate transporter LppX OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=lppX PE=1 SV=1 MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDA TKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISV KLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPAS SVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD |
Sequence length | 233 AA |
Subcellular Location | Membrane |
Protein Structure | |
PDB ID | 2BYO |
Glycosylation Status | |
Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
Literature | |
Year of Identification | 2009 |
Year of Identification Month Wise | 2009.2 |
Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
Corresponding Author | Clara Espitia |
Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |
Reference | González-Zamorano M, Mendoza-Hernández G, Xolalpa W, Parada C, Vallecillo AJ, Bigi F, Espitia C (2009) .Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins.J Proteome Res. 2009, 8(2), 721-33. [PubMed: 19196185] |
Author | Gonzalez-Zamorano, M., Mendoza-Hernandez, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C |
Research Group | Department of Immunology, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |
Corresponding Author | Espitia, C |
Contact | Department of Immunology, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |