ProGP273 (LppX (Putative lipoprotein))
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| ProGP ID | ProGP273 (LppX (Putative lipoprotein)) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium tuberculosis |
| Domain | Bacteria |
| Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
| Taxonomic ID (NCBI) | 1773 |
| Genome Information | |
| GenBank | AL123456.3 |
| EMBL | BX842581 |
| Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
| Gene Information | |
| Gene Name | lppX (Rv2945c) |
| NCBI Gene ID | 887956 |
| GenBank Gene Sequence | NC_000962.3 |
| Protein Information | |
| Protein Name | LppX (Putative lipoprotein) |
| UniProtKB/SwissProt ID | P9WK65 |
| NCBI RefSeq | WP_003414872.1 |
| EMBL-CDS | AL123456.3 |
| UniProtKB Sequence | >sp|P9WK65|LPPX_MYCTU Putative phthiocerol dimycocerosate transporter LppX OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=lppX PE=1 SV=1 MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDA TKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISV KLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPAS SVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD |
| Sequence length | 233 AA |
| Subcellular Location | Membrane |
| Protein Structure | |
| PDB ID | 2BYO |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
| Literature | |
| Year of Identification | 2009 |
| Year of Identification Month Wise | 2009.2 |
| Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
| Corresponding Author | Clara Espitia |
| Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |