ProGP276 (LpqF lipoprotein)

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ProGP ID ProGP276 (LpqF lipoprotein)
Validation Status Uncharacterized
Organism Information
Organism NameMycobacterium tuberculosis
Domain Bacteria
Classification Phylum : Actinobacteria
Class : Actinomycetia
Orders : Corynebacteriales
Family : Mycobacteriaceae
Genus : Mycobacterium
Species : tuberculosis
Taxonomic ID (NCBI) 1773
Genome Information
GenBank AL123456.3
EMBL BX842583
Organism Additional Information It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens.
Gene Information
Gene NamelpqF (Rv3593)
NCBI Gene ID 886290
GenBank Gene Sequence NC_000962.3
Protein Information
Protein NameLpqF lipoprotein
UniProtKB/SwissProt ID O06155
NCBI RefSeq NP_218110.1
EMBL-CDSAL123456.3
UniProtKB Sequence >tr|O06155|O06155_MYCTU PROBABLE CONSERVED LIPOPROTEIN LPQF OS=Mycobacterium tuberculosis GN=lpqF PE=4 SV=2 MGPARLHNRRAGRRMLALSAAAALIVALASGCSSAPTPSANAANHGHRIDTRTPPGLRAQ QTMDMLNSDWPIGEIGVGTLAAPGQVDTVKTTMEALWWDRPFALAGVDIGASVAALHLIS SYGAQQDIRIHTDDDGWVDRFDVETQAPSIASWRDVDAALSKTGARYSFQVAKVDNGRCD PVAGTNTGESLPLASIFKLYVLHALAGAVQHNTVSWDDLLTVTAKSKAVGSSGLELPVGA RVSVRTAAEKMIATSDNMATDLLIERLGTRAIEEALASAGHHDPASMTPFPTMYELFSVG WGKPDLRDQWKHATQQVRAQILRQTNSTPYQPDPTRAHTPASNYGAEWYGSAEDICRVHA ALRADAVGPASPVRQIMSAVPGIQLDRSVWPYIGAKAGGLPGDLTFSWYAVDKTGQPWVV SFQLNWPRDHGPTVTGWMLQVARQVFALIAPQ
Sequence length 452 AA
Function Lipoprotein
Glycosylation Status
Technique(s) used for Glycosylation DetectionConcanavalin A (ConA) binding
Literature
Year of Identification2009
Year of Identification Month Wise2009.2
ReferenceGonzález-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733.
Corresponding Author Clara Espitia
ContactImmunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico.