ProGP289 (Rv0281)
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ProGP ID | ProGP289 (Rv0281) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Mycobacterium tuberculosis |
Domain | Bacteria |
Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
Taxonomic ID (NCBI) | 1773 |
Genome Information | |
GenBank | AL123456.3 |
EMBL | BX842572 |
Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
Gene Information | |
Gene Name | Rv0281 |
NCBI Gene ID | 886618 |
GenBank Gene Sequence | NC_000962.3 |
Protein Information | |
Protein Name | Rv0281 |
UniProtKB/SwissProt ID | P9WFI9 |
NCBI RefSeq | WP_003401448.1 |
EMBL-CDS | AL123456.3 |
UniProtKB Sequence | >sp|P9WFI9|Y293_MYCTU Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0281 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv0281 PE=1 SV=1 MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKL PDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGT TVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAE GLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHP FFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAA RV |
Sequence length | 302 AA |
Function | Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0281/MT0293. |
Glycosylation Status | |
Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
Literature | |
Year of Identification | 2009 |
Year of Identification Month Wise | 2009.2 |
Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
Corresponding Author | Clara Espitia |
Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |