ProGP294 (Secreted protease)
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ProGP ID | ProGP294 (Secreted protease) |
Validation Status | Uncharacterized |
Organism Information | |
Organism Name | Mycobacterium tuberculosis |
Domain | Bacteria |
Classification | Phylum : Actinobacteria Class : Actinomycetia Orders : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium Species : tuberculosis |
Taxonomic ID (NCBI) | 1773 |
Genome Information | |
GenBank | AL123456.3 |
EMBL | BX842580 |
Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
Gene Information | |
Gene Name | Rv2672 |
NCBI Gene ID | 887398 |
GenBank Gene Sequence | NC_000962.3 |
Protein Information | |
Protein Name | Secreted protease |
UniProtKB/SwissProt ID | P71969 |
NCBI RefSeq | NP_217188.1 |
EMBL-CDS | AL123456.3 |
UniProtKB Sequence | >tr|P71969|P71969_MYCTU POSSIBLE SECRETED PROTEASE OS=Mycobacterium tuberculosis GN=Rv2672 PE=4 SV=1 MATVVGMSRPMTSTAMLVALTCSATVLAACVPAFGADPRFATYSGAGPQGAATTTPPPAG PPPLAAPKNDLSWHDCTSRVYSNAGIPAAPGVKLECASYDTDLDPLVGGSTAVSIGVVRA RSNQTPSDAGPLVFTTGSDLPSSTQLPVWLAHAGIDVLRSHPIVAVDRRGMGMSSPIDCR DHFDRDEMRDQAQFQAGDDPVANLSDISNTATTDCTDAIAPGESAYDNTHAASDIERLRK LWDVPALAFVGIGNGTQVALAYAASRPDNVARLILDSPIALGVSAEAAAEQQVQGQQAAL DAFAAQCVAVNCALGSHPKGAVSALLSAARSGDGPGGASVAAVANAVATALGFPDSGRVD STTKLADALAAARSGDMNLLSALINRADTTRDTDGQFISSCSDAVNRPTPDRVRELVVAW GKLYPQFGAVAALNLVKCVHWPSSSPPQPPKDLKVDVLLLGVQNDPIVGNEGVAATAATA INANAASKRVMWQGIGHGASIYSSCAVPPLVAYLDTGKLPDTDTYCPA |
Sequence length | 528 AA |
Glycosylation Status | |
Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
Literature | |
Year of Identification | 2009 |
Year of Identification Month Wise | 2009.2 |
Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
Corresponding Author | Clara Espitia |
Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |