ProGP320 (LppC)
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| ProGP ID | ProGP320 (LppC) |
| Validation Status | Uncharacterized |
| Organism Information | |
| Organism Name | Mycobacterium tuberculosis |
| Domain | Bacteria |
| Classification | Family: Mycobacteriaceae Suborder: Corynebacterineae Order: Actinomycetales Subclass: Actinobacteridae Class: Actinobacteria Division or phylum: "Actinobacteria" |
| Taxonomic ID (NCBI) | 1773 |
| Genome Information | |
| GenBank | BX842578.1 |
| EMBL | BX842578 |
| Organism Additional Information | It is the causative agent of human tuberculosis. The pathogenesis is influenced by its lipoglycans and glycolipids (having a wide range of immunomodulatory activities), and a variety of its virulence factors and antigens. |
| Gene Information | |
| Gene Name | lppC (Rv1911c) |
| NCBI Gene ID | 885646 |
| GenBank Gene Sequence | NC_000962.2 |
| Protein Information | |
| Protein Name | LppC |
| UniProtKB/SwissProt ID | P9WFN3 |
| NCBI RefSeq | WP_003409568.1 |
| EMBL-CDS | CCP44678.1 |
| UniProtKB Sequence | >sp|P9WFN3|LPPC_MYCTU Putative lipoprotein LppC OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=lppC PE=1 SV=2 MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIAS PMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPG SGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQ AAQAIAQAASGQARLVGTFEG |
| Sequence length | 205 AA |
| Function | Lipoprotein |
| Glycosylation Status | |
| Technique(s) used for Glycosylation Detection | Concanavalin A (ConA) binding |
| Literature | |
| Year of Identification | 2009 |
| Year of Identification Month Wise | 2000.5 |
| Reference | González-Zamorano, M., Mendoza-Hernández, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C., 2009. Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. Journal of proteome research, 8(2), pp.721-733. |
| Corresponding Author | Clara Espitia |
| Contact | Immunology Department, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |
| Reference | Gonzalez-Zamorano, M., Mendoza-Hernandez, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C. (2009) Mycobacterium tuberculosis glycoproteomics based on ConA-lectin affinity capture of mannosylated proteins. J Proteome Res, 8, 721-733. [PubMed: 19196185] |
| Author | Gonzalez-Zamorano, M., Mendoza-Hernandez, G., Xolalpa, W., Parada, C., Vallecillo, A.J., Bigi, F. and Espitia, C |
| Research Group | Department of Immunology, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |
| Corresponding Author | Espitia, C |
| Contact | Department of Immunology, Institute of Biomedical Research, National Autonomous University of Mexico, Mexico. |